AIMC Topic: Cluster Analysis

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Cross modality learning of cell painting and transcriptomics data improves mechanism of action clustering and bioactivity modelling.

Scientific reports
In drug discovery, different data modalities (chemical structure, cell biology, quantum mechanics, etc.) are abundant, and their integration can help with understanding aspects of chemistry, biology, and their interactions. Within cell biology, cell ...

Clustering cell nuclei on microgrooves for disease diagnosis using deep learning.

Scientific reports
Various diseases including laminopathies and certain types of cancer are associated with abnormal nuclear mechanical properties that influence cellular and nuclear deformations in complex environments. Recently, microgroove substrates designed to mim...

A Machine Learning-Based Clustering Analysis to Explore Bisphenol A and Phthalate Exposure from Medical Devices in Infants with Congenital Heart Defects.

Environmental health perspectives
BACKGROUND: Plastic-containing medical devices are commonly used in critical care units and other patient care settings. Patients are often exposed to xenobiotic agents that are leached out from plastic-containing medical devices, including bisphenol...

scGANSL: Graph Attention Network with Subspace Learning for scRNA-seq Data Clustering.

Journal of chemical information and modeling
Single-cell RNA sequencing (scRNA-seq) has become a crucial technology for analyzing cellular diversity at the single-cell level. Cell clustering is crucial in scRNA-seq data analysis as it accurately identifies distinct cell types and uncovers poten...

Analysis of IPV success treatment from an AI approach.

PloS one
Intimate partner violence (IPV) is a serious social problem in Chile. Understanding the patterns of internalization and the motivations maintaining it is crucial to design optimal treatments that ensure adherence and completeness. This, in addition, ...

Multi-view clustering via global-view graph learning.

PloS one
Multiview clustering aims to improve clustering performance by exploring multiple representations of data and has become an important research direction. Meanwhile, graph-based methods have been extensively studied and have shown promising performanc...

EODA: A three-stage efficient outlier detection approach using Boruta-RF feature selection and enhanced KNN-based clustering algorithm.

PloS one
Outlier detection is essential for identifying unusual patterns or observations that significantly deviate from the normal behavior of a dataset. With the rapid growth of data science, the prevalence of anomalies and outliers has increased, which can...

Relapse prediction using wearable data through convolutional autoencoders and clustering for patients with psychotic disorders.

Scientific reports
Relapse of psychotic disorders occurs commonly even after appropriate treatment. Digital phenotyping becomes essential to achieve remote monitoring for mental conditions. We applied a personalized approach using neural-network-based anomaly detection...

Automating the Analysis of Substrate Reactivity through Environment Interaction Mapping.

Journal of chemical information and modeling
Exploring the interaction configurations between substrates and atomic or molecular systems is crucial for various scientific and technological applications, such as characterizing catalytic reactions, solvation structures, and molecular interactions...

Leveraging Digital Twins for Stratification of Patients with Breast Cancer and Treatment Optimization in Geriatric Oncology: Multivariate Clustering Analysis.

JMIR cancer
BACKGROUND: Defining optimal adjuvant therapeutic strategies for older adult patients with breast cancer remains a challenge, given that this population is often overlooked and underserved in clinical research and decision-making tools.