AIMC Topic: Cognitive Dysfunction

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Modelling prognostic trajectories of cognitive decline due to Alzheimer's disease.

NeuroImage. Clinical
Alzheimer's disease (AD) is characterised by a dynamic process of neurocognitive changes from normal cognition to mild cognitive impairment (MCI) and progression to dementia. However, not all individuals with MCI develop dementia. Predicting whether ...

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment.

Journal of visualized experiments : JoVE
Mild cognitive impairment (MCI) is the first sign of dementia among elderly populations and its early detection is crucial in our aging societies. Common MCI tests are time-consuming such that indiscriminate massive screening would not be cost-effect...

A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease.

NeuroImage
Alzheimer's disease (AD) is a progressive and irreversible brain degenerative disorder. Mild cognitive impairment (MCI) is a clinical precursor of AD. Although some treatments can delay its progression, no effective cures are available for AD. Accura...

Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review.

Psychiatry research
Preserving cognition and mental capacity is critical to aging with autonomy. Early detection of pathological cognitive decline facilitates the greatest impact of restorative or preventative treatments. Artificial Intelligence (AI) in healthcare is th...

Cognitive signature of brain FDG PET based on deep learning: domain transfer from Alzheimer's disease to Parkinson's disease.

European journal of nuclear medicine and molecular imaging
PURPOSE: Although functional brain imaging has been used for the early and objective assessment of cognitive dysfunction, there is a lack of generalized image-based biomarker which can evaluate individual's cognitive dysfunction in various disorders....

Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data.

BMC medical informatics and decision making
BACKGROUND: Neuropsychological tests (NPTs) are important tools for informing diagnoses of cognitive impairment (CI). However, interpreting NPTs requires specialists and is thus time-consuming. To streamline the application of NPTs in clinical settin...

A distributed multitask multimodal approach for the prediction of Alzheimer's disease in a longitudinal study.

NeuroImage
Predicting the progression of Alzheimer's Disease (AD) has been held back for decades due to the lack of sufficient longitudinal data required for the development of novel machine learning algorithms. This study proposes a novel machine learning algo...

Effects of robotic neurorehabilitation through lokomat plus virtual reality on cognitive function in patients with traumatic brain injury: A retrospective case-control study.

The International journal of neuroscience
Traumatic brain injury (TBI) is a clinical condition characterized by damage due to a mechanical physical event, which has a devastating impact on both the patient and his/her family. The purpose of this study is to evaluate the effects of robotic n...

Developing assistive robots for people with mild cognitive impairment and mild dementia: a qualitative study with older adults and experts in aged care.

BMJ open
OBJECTIVES: This research is part of an international project to design and test a home-based healthcare robot to help older adults with mild cognitive impairment (MCI) or early dementia. The aim was to investigate the perceived usefulness of differe...