AIMC Topic: Colitis, Ulcerative

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Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study.

The lancet. Gastroenterology & hepatology Nov 29, 2021
BACKGROUND: A combination of endoscopic and histological evaluation is important in the management of patients with ulcerative colitis. We aimed to adapt our previous deep neural network system (deep neural ulcerative colitis [DNUC]) to full video co...
Colitis, Ulcerative Intestinal Mucosa Biopsy Remission Induction Video Recording Sensitivity and Specificity Cross-Sectional Studies Male Middle Aged Colonoscopy Random Allocation Humans Neural Networks, Computer Prospective Studies Female Adult
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Identification of diagnostic signatures in ulcerative colitis patients via bioinformatic analysis integrated with machine learning.

Human cell Nov 3, 2021
Ulcerative colitis (UC) is an immune-related disorder with enhanced prevalence globally. Early diagnosis is critical for the effective treatment of UC. However, it still lacks specific diagnostic signatures. The aim of our study was to explore effici...
Logistic Models Colitis, Ulcerative Gene Expression Lithostathine alpha-Defensins Pancreatitis-Associated Proteins Humans Machine Learning Genetic Association Studies Computational Biology
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Machine learning using clinical data at baseline predicts the efficacy of vedolizumab at week 22 in patients with ulcerative colitis.

Scientific reports Aug 12, 2021
Predicting the response of patients with ulcerative colitis (UC) to a biologic such as vedolizumab (VDZ) before administration is an unmet need for optimizing individual patient treatment. We hypothesized that the machine-learning approach with daily...
Humans Antibodies, Monoclonal, Humanized Colitis, Ulcerative Gastrointestinal Agents Remission Induction Machine Learning Young Adult Proof of Concept Study Retrospective Studies Adult Female Male Aged Middle Aged Aged, 80 and over Adolescent
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Deep Neural Network Accurately Predicts Prognosis of Ulcerative Colitis Using Endoscopic Images.

Gastroenterology Jan 21, 2021
Young Adult Adult Male Middle Aged Colonoscopy Prognosis Female Hospitalization Aged Aged, 80 and over Colitis, Ulcerative Intestinal Mucosa Predictive Value of Tests Colectomy Steroids Severity of Illness Index Adolescent Follow-Up Studies Wound Healing Humans Neural Networks, Computer
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Development of a susceptibility gene based novel predictive model for the diagnosis of ulcerative colitis using random forest and artificial neural network.

Aging Oct 24, 2020
Ulcerative colitis is a type of inflammatory bowel disease characterized by chronic and recurrent nonspecific inflammation of the intestinal tract. To find susceptibility genes and develop a novel predictive model of ulcerative colitis, two sets of c...
Humans Neural Networks, Computer Models, Genetic Retrospective Studies Colitis, Ulcerative Genetic Predisposition to Disease
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Central Reading of Ulcerative Colitis Clinical Trial Videos Using Neural Networks.

Gastroenterology Oct 21, 2020
BACKGROUND AND AIMS: Endoscopic disease activity scoring in ulcerative colitis (UC) is useful in clinical practice but done infrequently. It is required in clinical trials, where it is expensive and slow because human central readers are needed. A ma...
Antibodies, Monoclonal, Humanized Colitis, Ulcerative Intestinal Mucosa Predictive Value of Tests Feasibility Studies Video Recording Image Interpretation, Computer-Assisted Observer Variation Colonoscopy Severity of Illness Index Deep Learning Adolescent Treatment Outcome Young Adult Adult Male Middle Aged Colon Prospective Studies Female Aged Humans
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Development and Validation of a Deep Neural Network for Accurate Evaluation of Endoscopic Images From Patients With Ulcerative Colitis.

Gastroenterology Feb 12, 2020
BACKGROUND & AIMS: There are intra- and interobserver variations in endoscopic assessment of ulcerative colitis (UC) and biopsies are often collected for histologic evaluation. We sought to develop a deep neural network system for consistent, objecti...
Female Reproducibility of Results Aged Aged, 80 and over Young Adult Image Interpretation, Computer-Assisted Adult Male Humans Middle Aged Colon Severity of Illness Index Wound Healing Colonoscopy Databases, Factual Diagnosis, Computer-Assisted Colitis, Ulcerative Deep Learning Prospective Studies Predictive Value of Tests Adolescent Biopsy Treatment Outcome Remission Induction
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Performance of a Deep Learning Model vs Human Reviewers in Grading Endoscopic Disease Severity of Patients With Ulcerative Colitis.

JAMA network open May 3, 2019
IMPORTANCE: Assessing endoscopic disease severity in ulcerative colitis (UC) is a key element in determining therapeutic response, but its use in clinical practice is limited by the requirement for experienced human reviewers.
Humans Retrospective Studies Colitis, Ulcerative Female Video Recording Male Reproducibility of Results Middle Aged Adult Colonoscopy Severity of Illness Index Deep Learning
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Novel computer-assisted diagnosis system for endoscopic disease activity in patients with ulcerative colitis.

Gastrointestinal endoscopy Oct 24, 2018
BACKGROUND AND AIMS: Evaluation of endoscopic disease activity for patients with ulcerative colitis (UC) is important when determining the treatment of choice. However, endoscopists require a certain period of training to evaluate the activity of inf...
Adult Male Middle Aged Colonoscopy Diagnosis, Computer-Assisted Algorithms Female Aged Aged, 80 and over Humans Young Adult Adolescent Neural Networks, Computer ROC Curve Colitis, Ulcerative Intestinal Mucosa Area Under Curve
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Fully automated diagnostic system with artificial intelligence using endocytoscopy to identify the presence of histologic inflammation associated with ulcerative colitis (with video).

Gastrointestinal endoscopy Sep 27, 2018
BACKGROUND AND AIMS: In the treatment of ulcerative colitis (UC), an incremental benefit of achieving histologic healing beyond that of endoscopic mucosal healing has been suggested; persistent histologic inflammation increases the risk of exacerbati...
Colon Colonoscopy Diagnosis, Computer-Assisted Inflammation Intestinal Mucosa Female Humans Colitis, Ulcerative Rectum Reproducibility of Results Artificial Intelligence Automation Sensitivity and Specificity Machine Learning Algorithms Male Retrospective Studies Middle Aged
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