Bioinformatic annotation of protein function is essential but extremely sophisticated, which asks for extensive efforts to develop effective prediction method. However, the existing methods tend to amplify the representativeness of the families with ...
The development of a new vaccine is a challenging exercise involving several steps including computational studies, experimental work, and animal studies followed by clinical studies. To accelerate the process, in silico screening is frequently used ...
N-methylguanosine (m7G) is an essential, ubiquitous, and positively charged modification at the 5' cap of eukaryotic mRNA, modulating its export, translation, and splicing processes. Although several machine learning (ML)-based computational predicto...
BACKGROUND: Parkinson's disease (PD) is a neurological disorder that is marked by the deficit of neurons in the midbrain that changes motor and cognitive function. In the substantia nigra, the selective demise of dopamine-producing neurons was the ma...
Link weight prediction is an important subject in network science and machine learning. Its applications to social network analysis, network modeling, and bioinformatics are ubiquitous. Although this subject has attracted considerable attention recen...
Neural networks : the official journal of the International Neural Network Society
Mar 10, 2022
Graph Neural Networks (GNNs) are powerful architectures for learning on graphs. They are efficient for predicting nodes, links and graphs properties. Standard GNN variants follow a message passing schema to update nodes representations using informat...
Computational and mathematical methods in medicine
Mar 10, 2022
This study was aimed at exploring the effect of ultrasound image evaluation of comprehensive nursing scheme based on artificial intelligence algorithms on patients with diabetic kidney disease (DKD). 44 patients diagnosed with DKD were randomly divid...
Journal of bioinformatics and computational biology
Mar 9, 2022
Enhancers are short regulatory DNA fragments that are bound with proteins called activators. They are free-bound and distant elements, which play a vital role in controlling gene expression. It is challenging to identify enhancers and their strength ...
Proceedings of the National Academy of Sciences of the United States of America
Mar 7, 2022
SignificanceComputational protein design promises to advance applications in medicine and biotechnology by creating proteins with many new and useful functions. However, new functions require the design of specific and often irregular atom-level geom...
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