AIMC Topic: Computational Biology

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Enhancing Privacy-Preserving Cancer Classification with Convolutional Neural Networks.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Precision medicine significantly enhances patients prognosis, offering personalized treatments. Particularly for metastatic cancer, incorporating primary tumor location into the diagnostic process greatly improves survival rates. However, traditional...

Biologically Enhanced Machine Learning Model to uncover Novel Gene-Drug Targets for Alzheimer's Disease.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Given the complexity and multifactorial nature of Alzheimer's disease, investigating potential drug-gene targets is imperative for developing effective therapies and advancing our understanding of the underlying mechanisms driving the disease. We pre...

Understanding TCR T cell knockout behavior using interpretable machine learning.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Genetic perturbation of T cell receptor (TCR) T cells is a promising method to unlock better TCR T cell performance to create more powerful cancer immunotherapies, but understanding the changes to T cell behavior induced by genetic perturbations rema...

ClinValAI: A framework for developing Cloud-based infrastructures for the External Clinical Validation of AI in Medical Imaging.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Artificial Intelligence (AI) algorithms showcase the potential to steer a paradigm shift in clinical medicine, especially medical imaging. Concerns associated with model generalizability and biases necessitate rigorous external validation of AI algor...

Investigating the Differential Impact of Psychosocial Factors by Patient Characteristics and Demographics on Veteran Suicide Risk Through Machine Learning Extraction of Cross-Modal Interactions.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Accurate prediction of suicide risk is crucial for identifying patients with elevated risk burden, helping ensure these patients receive targeted care. The US Department of Veteran Affairs' suicide prediction model primarily leverages structured elec...

Implications of An Evolving Regulatory Landscape on the Development of AI and ML in Medicine.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
The rapid advancement of artificial intelligence and machine learning (AI/ML) technologies in healthcare presents significant opportunities for enhancing patient care through innovative diagnostic tools, monitoring systems, and personalized treatment...

Automated Evaluation of Antibiotic Prescribing Guideline Concordance in Pediatric Sinusitis Clinical Notes.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
BACKGROUND: Ensuring antibiotics are prescribed only when necessary is crucial for maintaining their effectiveness and is a key focus of public health initiatives worldwide. In cases of sinusitis, among the most common reasons for antibiotic prescrip...

Artificial Allies: Validation of Synthetic Text for Peer Support Tools through Data Augmentation in NLP Model Development.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
This study investigates the potential of using synthetic text to augment training data for Natural Language Processing (NLP) models, specifically within the context of peer support tools. We surveyed 22 participants-13 professional peer supporters an...

A Visual Analytics Framework for Assessing Interactive AI for Clinical Decision Support.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Human involvement remains critical in most instances of clinical decision-making. Recent advances in AI and machine learning opened the door for designing, implementing, and translating interactive AI systems to support clinicians in decision-making....

Session Introduction: AI and Machine Learning in Clinical Medicine: Generative and Interactive Systems at the Human-Machine Interface.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Artificial Intelligence (AI) technologies are increasingly capable of processing complex and multilayered datasets. Innovations in generative AI and deep learning have notably enhanced the extraction of insights from both unstructured texts, images, ...