Journal of chemical information and modeling
Aug 19, 2025
Nephrotoxicity remains a critical safety concern in drug development and clinical practice. Despite their significance, existing computational models for nephrotoxicity prediction face challenges related to limited precision and reliability. To addre...
AIM: Timely intervention of interstitial lung disease (ILD) was promising for attenuating the lung function decline and improving clinical outcomes. The prone position HRCT is essential for early diagnosis of ILD, but limited by its high radiation ex...
Cancer imaging : the official publication of the International Cancer Imaging Society
Aug 19, 2025
OBJECTIVE: This study aimed to construct a multimodal imaging deep learning (DL) model integrating mpMRI and F-PSMA-PET/CT for the prediction of extraprostatic extension (EPE) in prostate cancer, and to assess its effectiveness in enhancing the diagn...
BACKGROUND: Accurate identification of translation initiation sites is essential for the proper translation of mRNA into functional proteins. In eukaryotes, the choice of the translation initiation site is influenced by multiple factors, including it...
This work intends to drive reform and innovation in English teaching evaluation and support personalized English instruction. It utilizes deep learning (DL) and artificial intelligence (AI)-driven data mining technology to explore a reliable and effi...
Eye diseases can affect vision and well-being, so early, accurate diagnosis is crucial to prevent serious impairment. Deep learning models have shown promise for automating the diagnosis of eye diseases from images. However, current methods mostly us...
This study compared an automated deep learning algorithm with certified human graders from the Vienna Reading Center (VRC) in identifying intra- (IRF) and subretinal fluid (SRF) in OCT scans of patients treated for neovascular age-related macular deg...
The spatial organization of cells plays a pivotal role in shaping tissue functions and phenotypes in various biological systems and diseased microenvironments. However, the topological principles governing interactions among cell types within spatial...
OBJECTIVES: This study aims to develop a deep learning algorithm (DLA) using the InceptionV3 architecture for effective diabetic peripheral neuropathy (DPN) screening via corneal confocal microscopy (CCM) images.
Journal of chemical information and modeling
Aug 18, 2025
Antimicrobial peptides (AMPs) have emerged as vital candidates in the fight against antibiotic resistance. The traditional processes for AMP design and discovery are often time-consuming and inefficient. Here, we propose the AMPGP model, which employ...
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