AIMC Topic: Deep Learning

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Mapping the learning curves of deep learning networks.

PLoS computational biology
There is an important challenge in systematically interpreting the internal representations of deep neural networks (DNNs). Existing techniques are often less effective for non-tabular tasks, or they primarily focus on qualitative, ad-hoc interpretat...

SleepECG-Net: Explainable Deep Learning Approach With ECG for Pediatric Sleep Apnea Diagnosis.

IEEE journal of biomedical and health informatics
Obstructive sleep apnea (OSA) in children is a prevalent and serious respiratory condition linked to cardiovascular morbidity. Polysomnography, the standard diagnostic approach, faces challenges in accessibility and complexity, leading to underdiagno...

M-NET: Transforming Single Nucleotide Variations Into Patient Feature Images for the Prediction of Prostate Cancer Metastasis and Identification of Significant Pathways.

IEEE journal of biomedical and health informatics
High-performance prediction of prostate cancer metastasis based on single nucleotide variations remains a challenge. Therefore, we developed a novel biologically informed deep learning framework, named M-NET, for the prediction of prostate cancer met...

ADR-DQPU: A Novel ADR Signal Detection Using Deep Reinforcement and Positive-Unlabeled Learning.

IEEE journal of biomedical and health informatics
The medical community has grappled with the challenge of analysis and early detection of severe and unknown adverse drug reactions (ADRs) from Spontaneous Reporting Systems (SRSs) like the FDA Adverse Event Reporting System (FAERS), which often lack ...

UnBias: Unveiling Bias Implications in Deep Learning Models for Healthcare Applications.

IEEE journal of biomedical and health informatics
The rapid integration of deep learning-powered artificial intelligence systems in diverse applications such as healthcare, credit assessment, employment, and criminal justice has raised concerns about their fairness, particularly in how they handle v...

CellCircLoc: Deep Neural Network for Predicting and Explaining Cell Line-Specific CircRNA Subcellular Localization.

IEEE journal of biomedical and health informatics
The subcellular localization of circular RNAs (circRNAs) is crucial for understanding their functional relevance and regulatory mechanisms. CircRNA subcellular localization exhibits variations across different cell lines, demonstrating the diversity ...

Forecasting Epidemic Spread With Recurrent Graph Gate Fusion Transformers.

IEEE journal of biomedical and health informatics
Predicting the unprecedented, nonlinear nature of COVID-19 presents a significant public health challenge. Recent advances in deep learning, such as graph neural networks (GNNs), recurrent neural networks (RNNs), and Transformers, have enhanced predi...

A Multimodal Consistency-Based Self-Supervised Contrastive Learning Framework for Automated Sleep Staging in Patients With Disorders of Consciousness.

IEEE journal of biomedical and health informatics
Sleep is a fundamental human activity, and automated sleep staging holds considerable investigational potential. Despite numerous deep learning methods proposed for sleep staging that exhibit notable performance, several challenges remain unresolved,...

Attention-Based Q-Space Deep Learning Generalized for Accelerated Diffusion Magnetic Resonance Imaging.

IEEE journal of biomedical and health informatics
Diffusion magnetic resonance imaging (dMRI) is a non-invasive method for capturing the microanatomical information of tissues by measuring the diffusion weighted signals along multiple directions, which is widely used in the quantification of microst...

Interpretable Dynamic Directed Graph Convolutional Network for Multi-Relational Prediction of Missense Mutation and Drug Response.

IEEE journal of biomedical and health informatics
Tumor heterogeneity presents a significant challenge in predicting drug responses, especially as missense mutations within the same gene can lead to varied outcomes such as drug resistance, enhanced sensitivity, or therapeutic ineffectiveness. These ...