Langmuir : the ACS journal of surfaces and colloids
Jun 3, 2025
The surface chemistry of nanomaterials, particularly the density of functional groups, governs their behavior in applications such as bioanalysis, bioimaging, and environmental impact studies. Here, we report a precise method to quantify carboxyl gro...
It is an exciting time for researchers working to link proteins to their functions. Most techniques for extracting functional information from genomic sequences were developed several years ago, with major progress driven by the availability of big d...
Fluorescence lifetime imaging microscopy (FLIM) has been widely used as an essential multiplexing and sensing tool in frontier fields such as materials science and life sciences. However, the accuracy of lifetime estimation is compromised by limited ...
Chembiochem : a European journal of chemical biology
Jun 3, 2025
H nuclear magnetic resonance (NMR) spectroscopy plays an important role in the pharmaceutical industry, but for complex substances, spectral analysis is challenging due to the narrow chemical shift range and signal splitting caused by scalar coupling...
Concurrent neurodegenerative and vascular pathologies pose a diagnostic challenge in the clinical setting, with histopathology remaining the definitive modality for dementia-type diagnosis. To address this clinical challenge, we introduce a neuropath...
Translational vision science & technology
Jun 2, 2025
PURPOSE: Standard deep learning (DL) models often suffer significant performance degradation on out-of-distribution (OOD) data, where test data differs from training data, a common challenge in medical imaging due to real-world variations.
MOTIVATION: Drug side effects refer to harmful or adverse reactions that occur during drug use, unrelated to the therapeutic purpose. A core issue in drug side effect prediction is determining the frequency of these drug side effects in the populatio...
MOTIVATION: Advances in high throughput technologies enabled large access to various types of omics. Each omics provides a partial view of the underlying biological process. Integrating multiple omics layers would help have a more accurate diagnosis....
BACKGROUND AND AIMS: Accurate near-term prediction of life-threatening ventricular arrhythmias would enable pre-emptive actions to prevent sudden cardiac arrest/death. A deep learning-enabled single-lead ambulatory electrocardiogram (ECG) may identif...
Characterizing cancer presents a delicate challenge as it involves deciphering complex biological interactions within the tumor's microenvironment. Clinical trials often provide histology images and molecular profiling of tumors, which can help under...
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