AIMC Topic: Deep Learning

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BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions.

Journal of chemical theory and computation
Enzyme-substrate interactions are essential to both biological processes and industrial applications. Advanced machine learning techniques have significantly accelerated biocatalysis research, revolutionizing the prediction of biocatalytic activities...

F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution.

Journal of medicinal chemistry
Fluorine (F) substitution is a common method of drug discovery and development. However, there are no accurate approaches available for predicting the bioactivity changes after F-substitution, as the effect of substitution on the interactions between...

PoachNet: Predicting Poaching Using an Ontology-Based Knowledge Graph.

Sensors (Basel, Switzerland)
Poaching poses a significant threat to wildlife and their habitats, necessitating advanced tools for its prediction and prevention. Existing tools for poaching prediction face challenges such as inconsistent poaching data, spatiotemporal complexity, ...

Enhancing classification of active and non-active lesions in multiple sclerosis: machine learning models and feature selection techniques.

BMC medical imaging
INTRODUCTION: Gadolinium-based T1-weighted MRI sequence is the gold standard for the detection of active multiple sclerosis (MS) lesions. The performance of machine learning (ML) and deep learning (DL) models in the classification of active and non-a...

Quantifying interpretation reproducibility in Vision Transformer models with TAVAC.

Science advances
Deep learning algorithms can extract meaningful diagnostic features from biomedical images, promising improved patient care in digital pathology. Vision Transformer (ViT) models capture long-range spatial relationships and offer robust prediction pow...

Automated Identification of Breast Cancer Relapse in Computed Tomography Reports Using Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: Breast cancer relapses are rarely collected by cancer registries because of logistical and financial constraints. Hence, we investigated natural language processing (NLP), enhanced with state-of-the-art deep learning transformer tools and la...

Accelerating antimicrobial peptide design: Leveraging deep learning for rapid discovery.

PloS one
Antimicrobial peptides (AMPs) are excellent at fighting many different infections. This demonstrates how important it is to make new AMPs that are even better at eliminating infections. The fundamental transformation in a variety of scientific discip...

Evaluation of a deep learning prostate cancer detection system on biparametric MRI against radiological reading.

European radiology
OBJECTIVES: This study aims to evaluate a deep learning pipeline for detecting clinically significant prostate cancer (csPCa), defined as Gleason Grade Group (GGG) ≥ 2, using biparametric MRI (bpMRI) and compare its performance with radiological read...

Intrinsic plasticity coding improved spiking actor network for reinforcement learning.

Neural networks : the official journal of the International Neural Network Society
Deep reinforcement learning (DRL) exploits the powerful representational capabilities of deep neural networks (DNNs) and has achieved significant success. However, compared to DNNs, spiking neural networks (SNNs), which operate on binary signals, mor...

A sparse and wide neural network model for DNA sequences.

Neural networks : the official journal of the International Neural Network Society
Accurate modeling of DNA sequences requires capturing distant semantic relationships between the nucleotide acid bases. Most existing deep neural network models face two challenges: (1) they are limited to short DNA fragments and cannot capture long-...