AIMC Topic: Deep Learning

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RNA3DB: A structurally-dissimilar dataset split for training and benchmarking deep learning models for RNA structure prediction.

Journal of molecular biology
With advances in protein structure prediction thanks to deep learning models like AlphaFold, RNA structure prediction has recently received increased attention from deep learning researchers. RNAs introduce substantial challenges due to the sparser a...

Who Are the Anatomic Outliers Undergoing Total Knee Arthroplasty? A Computed Tomography-Based Analysis of the Hip-Knee-Ankle Axis Across 1,352 Preoperative Computed Tomographies Using a Deep Learning and Computer Vision-Based Pipeline.

The Journal of arthroplasty
BACKGROUND: Dissatisfaction after total knee arthroplasty (TKA) ranges from 15 to 30%. While patient selection may be partially responsible, morphological and reconstructive challenges may be determinants. Preoperative computed tomography (CT) scans ...

Deep Learning-Derived Myocardial Strain.

JACC. Cardiovascular imaging
BACKGROUND: Echocardiographic strain measurements require extensive operator experience and have significant intervendor variability. Creating an automated, open-source, vendor-agnostic method to retrospectively measure global longitudinal strain (GL...

Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition.

Journal of applied toxicology : JAT
Cytochrome P450 (CYP) enzymes are involved in the metabolism of approximately 75% of marketed drugs. Inhibition of the major drug-metabolizing P450s could alter drug metabolism and lead to undesirable drug-drug interactions. Therefore, it is of great...

A deep learning model for translating CT to ventilation imaging: analysis of accuracy and impact on functional avoidance radiotherapy planning.

Japanese journal of radiology
PURPOSE: Radiotherapy planning incorporating functional lung images has the potential to reduce pulmonary toxicity. Free-breathing 4DCT-derived ventilation image (CTVI) may help quantify lung function. This study introduces a novel deep-learning mode...

Artificial intelligence and machine learning in axial spondyloarthritis.

Current opinion in rheumatology
PURPOSE OF REVIEW: To evaluate the current applications and prospects of artificial intelligence and machine learning in diagnosing and managing axial spondyloarthritis (axSpA), focusing on their role in medical imaging, predictive modelling, and pat...

Identifying depression-related topics in smartphone-collected free-response speech recordings using an automatic speech recognition system and a deep learning topic model.

Journal of affective disorders
BACKGROUND: Prior research has associated spoken language use with depression, yet studies often involve small or non-clinical samples and face challenges in the manual transcription of speech. This paper aimed to automatically identify depression-re...

FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics.

International journal of biological macromolecules
Phosphorylation modifications play important regulatory roles in most biological processes. However, the functional assignment for the vast majority of the identified phosphosites remains a major challenge. Here, we provide a deep learning framework ...

Benchmarking machine learning-based real-time respiratory signal predictors in 4D SBRT.

Medical physics
BACKGROUND: Stereotactic body radiotherapy of thoracic and abdominal tumors has to account for respiratory intrafractional tumor motion. Commonly, an external breathing signal is continuously acquired that serves as a surrogate of the tumor motion an...

Research progress in water quality prediction based on deep learning technology: a review.

Environmental science and pollution research international
Water, an invaluable and non-renewable resource, plays an indispensable role in human survival and societal development. Accurate forecasting of water quality involves early identification of future pollutant concentrations and water quality indices,...