AIMC Topic: Deep Learning

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ToxMPNN: A deep learning model for small molecule toxicity prediction.

Journal of applied toxicology : JAT
Machine learning (ML) has shown a great promise in predicting toxicity of small molecules. However, the availability of data for such predictions is often limited. Because of the unsatisfactory performance of models trained on a single toxicity endpo...

Automated curation of large-scale cancer histopathology image datasets using deep learning.

Histopathology
BACKGROUND: Artificial intelligence (AI) has numerous applications in pathology, supporting diagnosis and prognostication in cancer. However, most AI models are trained on highly selected data, typically one tissue slide per patient. In reality, espe...

Deep Learning based Retinal Vessel Caliber Measurement and the Association with Hypertension.

Current eye research
PURPOSE: To develop a highly efficient and fully automated method that measures retinal vessel caliber using digital retinal photographs and evaluate the association between retinal vessel caliber and hypertension.

Quantitative and Visual Analysis of Data Augmentation and Hyperparameter Optimization in Deep Learning-Based Segmentation of Low-Grade Glioma Tumors Using Grad-CAM.

Annals of biomedical engineering
This study executes a quantitative and visual investigation on the effectiveness of data augmentation and hyperparameter optimization on the accuracy of deep learning-based segmentation of LGG tumors. The study employed the MobileNetV2 and ResNet bac...

A deep learning based holistic diagnosis system for immunohistochemistry interpretation and molecular subtyping.

Neoplasia (New York, N.Y.)
BACKGROUND: Breast cancer in different molecular subtypes, which is determined by the overexpression rates of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), progesterone receptor (PR), and Ki67, exhibit distinct symptom char...

Deep-learning-based joint rigid and deformable contour propagation for magnetic resonance imaging-guided prostate radiotherapy.

Medical physics
BACKGROUND: Deep learning-based unsupervised image registration has recently been proposed, promising fast registration. However, it has yet to be adopted in the online adaptive magnetic resonance imaging-guided radiotherapy (MRgRT) workflow.

Biomimetic Deep Learning Networks With Applications to Epileptic Spasms and Seizure Prediction.

IEEE transactions on bio-medical engineering
OBJECTIVE: In this study, we present a novel biomimetic deep learning network for epileptic spasms and seizure prediction and compare its performance with state-of-the-art conventional machine learning models.

A Deep Learning-Based Integrated Framework for Quality-Aware Undersampled Cine Cardiac MRI Reconstruction and Analysis.

IEEE transactions on bio-medical engineering
Cine cardiac magnetic resonance (CMR) imaging is considered the gold standard for cardiac function evaluation. However, cine CMR acquisition is inherently slow and in recent decades considerable effort has been put into accelerating scan times withou...

Fully automated deep learning based auto-contouring of liver segments and spleen on contrast-enhanced CT images.

Scientific reports
Manual delineation of liver segments on computed tomography (CT) images for primary/secondary liver cancer (LC) patients is time-intensive and prone to inter/intra-observer variability. Therefore, we developed a deep-learning-based model to auto-cont...