AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Software testing of knowledge-based clinical decision support systems is challenging, labor intensive, and expensive; yet, testing is necessary since clinical applications have heightened consequences. Thoughtful test case selection improves testing ...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Over 75 million Americans have multiple concurrent chronic conditions and medical decision making for these patients is mostly based on retrospective cohort studies. Current methods to generate cohorts of patients with comorbidities are neither scala...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
A computational phenotype is a set of clinically relevant and interesting characteristics that describe patients with a given condition. Various machine learning methods have been proposed to derive phenotypes in an automatic, high-throughput manner....
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...
AIMS: Diabetic nephropathy (DN) is a serious microvascular complication of a longstanding hyperglycemia. This study aims to evaluate whether urinary neutrophil gelatinase-associated lipocalin (NGAL) and urinary Interleukin-18 possess a better diagnos...
Journal of diabetes and its complications
Nov 3, 2018
AIMS: Serum uric acid (UA) increases in patients with kidney disease due to the impaired UA clearance. The present study sought to evaluate the association between UA/creatinine ratio (UA/Cr) and renal disease progression in patients with type 2 diab...
AIMS: Recently, it was suggested that betatrophin has a role in controlling pancreatic β cell proliferation and lipid metabolism, however, its role in human subjects has not been established yet. The predicting role of betatrophin and MDA along with ...
OBJECTIVE: Metformin is the preferred first-line medication for management of type 2 diabetes and prediabetes. However, over a third of patients experience primary or secondary therapeutic failure. We developed machine learning models to predict whic...
Journal of diabetes science and technology
Sep 5, 2018
In the future artificial intelligence (AI) will have the potential to improve outcomes diabetes care. With the creation of new sensors for physiological monitoring sensors and the introduction of smart insulin pens, novel data relationships based on ...
Accurate and reliable prediction of clinical progression over time has the potential to improve the outcomes of chronic disease. The classical approach to analyzing longitudinal data is to use (generalized) linear mixed-effect models (GLMM). However,...