Central nervous system (CNS) involvement in primary Sjögren's syndrome (pSS), although less frequent, can lead to serious complications. Our study aimed to assess white matter (WM) tract integrity, identify specific regions of disruption, quantify di...
BACKGROUND: Maximal tumor resection with neurological preservation is central to brain tumor surgery. This study evaluates the integration of an artificial intelligence-based connectomics platform for surgical planning, with exploratory tractometry a...
Biomechanics and modeling in mechanobiology
Dec 12, 2025
Large-scale axonal dynamic simulation is critical to study white matter injury but is prohibitive in computational cost. We solve this challenge by training a convolutional neural network (CNN) that takes fiber strain profiles as inputs to instantly ...
BACKGROUND: Machine learning shows great potential in science but struggles with complex, high-dimensional multi-omics data. PD progression is long, diagnosed mainly by clinical signs. This paper proposes a novel decision fusion method to improve the...
BACKGROUND: Glioblastoma (GBM) is no longer regarded as a single disease, as distinct molecular subgroups exist, with the mesenchymal (MES) having the worst prognosis. As such, there is a critical need for noninvasive methods to determine GBM molecul...
Traditional brain connectivity studies have focused mainly on structural connectivity, often relying on tractography with diffusion MRI (dMRI) to reconstruct white matter pathways. In parallel, studies of functional connectivity have examined correla...
BACKGROUND: Fetal diffusion-weighted Magnetic Resonance Imaging (dMRI) represents a promising modality for the assessment of white matter fiber organization, microstructure and development during pregnancy. Over the past two decades, research using t...
BACKGROUND: Identifying key areas of brain dysfunction in mental illness is critical for developing precision diagnosis and treatment. This study aimed to develop region-specific brain aging trajectory prediction models using multimodal magnetic reso...
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by genetic predisposition and alterations in brain structural connectivity. While existing studies have established associations between genetic variants a...
Psychological resilience is influenced by both psychological and biological factors. However, the potential of using DNA methylation (DNAm) probes and brain imaging variables to predict psychological resilience remains unclear. This study aimed to in...
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