AIMC Topic: DNA Damage
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A Framework for Automatic Recognition of Cell Damage on Microscopic Images using Artificial Neural Networks.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2018
Despite several technological advances in the past years, the vast majority of microscopy examinations continue to be performed in a very laborious, time-consuming manner, requiring highly experienced personnel to spend several hours to visually exam...
Investigating the Generalizability of the MultiFlow ® DNA Damage Assay and Several Companion Machine Learning Models With a Set of 103 Diverse Test Chemicals.
Toxicological sciences : an official journal of the Society of Toxicology
Mar 1, 2018
The in vitro MultiFlow DNA Damage assay multiplexes p53, γH2AX, phospho-histone H3, and polyploidization biomarkers into 1 flow cytometric analysis (Bryce, S. M., Bernacki, D. T., Bemis, J. C., and Dertinger, S. D. (2016). Genotoxic mode of action pr...
In vitro assessment of the cytotoxic, DNA damaging, and cytogenetic effects of hydroquinone in human peripheral blood lymphocytes.
Arhiv za higijenu rada i toksikologiju
Dec 20, 2017
This study investigated the mechanisms of hydroquinone toxicity and assessed the relationships between its cytotoxic, genotoxic, and cytogenetic effects tested at 8, 140, and 280 μg mL-1 in human peripheral blood lymphocytes exposed for 24 h. The out...
NEUROPROTECTIVE EFFECT OF BOSWELLIA SERRATA AND ITS ACTIVE CONSTITUENT ACETYL 11-KETO-β-BOSWELLIC ACID AGAINST OXYGEN-GLUCOSE-SERUM DEPRIVATION-INDUCED CELL INJURY.
Acta poloniae pharmaceutica
May 1, 2017
Oxidative stress plays a key role in pathophysiology of brain ischemia. This study aimed to test whether B. serrata hydroalcoholic extract (BSE) and its active constituent 3-acetyl-1 1-keto-β-boswellic acid (AKBA) could protect neurons against ischem...
Protective effect of Yiguanjian decoction against DNA damage on concanavalin A-induced liver injury mice model.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Aug 1, 2016
OBJECTIVE: To investigate the inhibitory effect of Yiguanjian decoction (YD) on DNA damage in Concanavalin A (Con A)-induced liver injury mice model and to explain the possible mechanism.
Antigenotoxic and apoptotic activities of essential oil of Correa.
Indian journal of pharmacology
Jan 1, 2016
OBJECTIVE: To study antigenotoxic and apoptotic activities of hydrodistilled essential oil from the leaves of Correa.
[Enhanced radiosensitivity of H22 ascitic tumor to 12C6+ ions radiation in ultra-filtration extract mixture from Astragalus mongholicus-treated mice].
Yao xue xue bao = Acta pharmaceutica Sinica
Dec 1, 2015
This study was designed to investigate the impact of ultra-filtration extract mixture from Astragals mongholicus (UEMAM) o radiosensitivity of H22 ascitic tumor in mice to 12C6+ ions radiation. The H22 ascitic tumor model was established in mice by i...
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