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Double-Blind Method

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Comparative Analysis of the Efficacy of Intrathecal Fentanyl and Magnesium Sulphate as an Adjuvant to Bupivacaine: A Double-Blinded Randomized Controlled Trial.

Asian journal of anesthesiology
BACKGROUNDS: The duration and potency of the subarachnoid block (SAB) can be enhanced by incorporating spinal additives into local anesthetics. In this study, the effectiveness of intrathecal fentanyl and magnesium sulphate as adjuvant anesthetics to...

Evaluation of impact of epidural volume extension on the quality of spinal anaesthesia in patients undergoing proximal femoral nailing surgeries - randomized controlled study.

Anaesthesiology intensive therapy
INTRODUCTION: Epidural volume extension is technique aiming to mitigate spinal anaesthesia induced hypotension, by reducing the dose of local anaesthetics. The present study was executed to determine the effect of epidural volume extension subarachno...

Safety, tolerability, pharmacokinetics, and pharmacodynamics of oral JNJ-64794964, a TLR-7 agonist, in healthy adults.

Antiviral therapy
BACKGROUND: This Phase I, two-part, first-in-human study assessed safety/tolerability and pharmacokinetics/pharmacodynamics of single-ascending doses (SAD) and multiple doses (MD) of the oral toll-like receptor-7 agonist, JNJ-64794964 (JNJ-4964) in h...

Multimodal treatment efficacy differs in dependence of core symptom profiles in adult Attention-Deficit/Hyperactivity Disorder: An analysis of the randomized controlled COMPAS trial.

Journal of psychiatric research
There is broad consensus that to improve the treatment of adult Attention-Deficit/Hyperactivity Disorder (ADHD), the various therapy options need to be tailored more precisely to the individual patient's needs and specific symptoms. This post-hoc ana...

A feasible method to evaluate deformable image registration with deep learning-based segmentation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: We have developed a feasible method to evaluate deformable image registration using deep learning (DL)-based segmentation.

Cracking double-blind review: Authorship attribution with deep learning.

PloS one
Double-blind peer review is considered a pillar of academic research because it is perceived to ensure a fair, unbiased, and fact-centered scientific discussion. Yet, experienced researchers can often correctly guess from which research group an anon...