AIMC Topic: Drug Carriers

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Machine learning integrated with in vitro experiments for study of drug release from PLGA nanoparticles.

Scientific reports
This paper investigates delivery of encapsulated drug from poly lactic-co-glycolic micro-/nano-particles. Experimental data collected from about 50 papers are analyzed by machine learning algorithms including linear regression, principal component an...

Drug Release Nanoparticle System Design: Data Set Compilation and Machine Learning Modeling.

ACS applied materials & interfaces
Magnetic nanoparticles (NPs) are gaining significant interest in the field of biomedical functional nanomaterials because of their distinctive chemical and physical characteristics, particularly in drug delivery and magnetic hyperthermia applications...

Machine Learning-Driven Prediction, Preparation, and Evaluation of Functional Nanomedicines Via Drug-Drug Self-Assembly.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Small molecules as nanomedicine carriers offer advantages in drug loading and preparation. Selecting effective small molecules for stable nanomedicines is challenging. This study used artificial intelligence (AI) to screen drug combinations for self-...

Toward Resolving Heterogeneous Mixtures of Nanocarriers in Drug Delivery Systems through Light Scattering and Machine Learning.

ACS nano
Nanocarriers (NCs) have emerged as a revolutionary approach in targeted drug delivery, promising to enhance drug efficacy and reduce toxicity through precise targeting and controlled release mechanisms. Despite their potential, the clinical adoption ...

Deep Learning for the Accurate Prediction of Triggered Drug Delivery.

IEEE transactions on nanobioscience
The need to mitigate the adverse effects of chemotherapy has driven the exploration of innovative drug delivery approaches. One emerging trend in cancer treatment is the utilization of Drug Delivery Systems (DDSs), facilitated by nanotechnology. Nano...

Antibacterial effects of thyme oil loaded solid lipid and chitosan nano-carriers against Salmonella Typhimurium and Escherichia coli as food preservatives.

PloS one
OBJECTIVES: Escherichia coli and Salmonella Typhimurium are frequent causes of foodborne illness affecting many people annually. In order to develop natural antimicrobial agents against these microorganisms, thyme oil (TO) was considered as active an...

Artificial intelligence for personalized nanomedicine; from material selection to patient outcomes.

Expert opinion on drug delivery
INTRODUCTION: Artificial intelligence (AI) is changing the field of nanomedicine by exploring novel nanomaterials for developing therapies of high efficacy. AI works on larger datasets, finding sought-after nano-properties for different therapeutic a...

Computational analysis of controlled drug release from porous polymeric carrier with the aid of Mass transfer and Artificial Intelligence modeling.

Scientific reports
Controlled release of a desired drug from porous polymeric biomaterials was analyzed via computational method. The method is based on simulation of mass transfer and utilization of artificial intelligence (AI). This study explores the efficacy of thr...

Optimising the production of PLGA nanoparticles by combining design of experiment and machine learning.

International journal of pharmaceutics
Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable polymer in drug delivery and nanoparticle (NP) formulation due to its controlled drug release properties and safety profiles. Among the methods available for NP production, nanopreci...

Machine Learning-Empowered Real-Time Acoustic Trapping: An Enabling Technique for Increasing MRI-Guided Microbubble Accumulation.

Sensors (Basel, Switzerland)
Acoustic trap, using ultrasound interference to ensnare bioparticles, has emerged as a versatile tool for life sciences due to its non-invasive nature. Bolstered by magnetic resonance imaging's advances in sensing acoustic interference and tracking d...