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Dystonic Disorders

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Basal Ganglia dysfunctions in movement disorders: What can be learned from computational simulations.

Movement disorders : official journal of the Movement Disorder Society
The basal ganglia are a complex neuronal system that is impaired in several movement disorders, including Parkinson's disease, Huntington's disease, and dystonia. Empirical studies have provided valuable insights into the brain dysfunctions underlyin...

A neuromorphic model of motor overflow in focal hand dystonia due to correlated sensory input.

Journal of neural engineering
OBJECTIVE: Motor overflow is a common and frustrating symptom of dystonia, manifested as unintentional muscle contraction that occurs during an intended voluntary movement. Although it is suspected that motor overflow is due to cortical disorganizati...

Haptic Feedback Manipulation During Botulinum Toxin Injection Therapy for Focal Hand Dystonia Patients: A Possible New Assistive Strategy.

IEEE transactions on haptics
Abnormality of sensorimotor integration in the basal ganglia and cortex has been reported in the literature for patients with task-specific focal hand dystonia (FHD). In this study, we investigate the effect of manipulation of kinesthetic input in pe...

Perception of yips among professional Japanese golfers: perspectives from a network modelled approach.

Scientific reports
'Yips' in golf is a complex spectrum of anxiety and movement-disorder that affects competitive sporting performance. With unclear etiology and high prevalence documented in western literature, the perception and management of this psycho-neuromuscula...

Machine learning models for diagnosis of essential tremor and dystonic tremor using grey matter morphological networks.

Parkinsonism & related disorders
BACKGROUND: Essential tremor (ET) and dystonic tremor (DT) are the two most common tremor disorders, and misdiagnoses are very common due to similar tremor symptoms. In this study, we explore the structural network mechanisms of ET and DT using brain...

Motor assessment of X-linked dystonia parkinsonism via machine-learning-based analysis of wearable sensor data.

Scientific reports
X-linked dystonia parkinsonism (XDP) is a neurogenetic combined movement disorder involving both parkinsonism and dystonia. Complex, overlapping phenotypes result in difficulties in clinical rating scale assessment. We performed wearable sensor-based...