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Encephalitis

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Gene Ontology Curation of Neuroinflammation Biology Improves the Interpretation of Alzheimer's Disease Gene Expression Data.

Journal of Alzheimer's disease : JAD
BACKGROUND: Gene Ontology (GO) is a major bioinformatic resource used for analysis of large biomedical datasets, for example from genome-wide association studies, applied universally across biological fields, including Alzheimer's disease (AD) resear...

Deep Learning-Enabled Identification of Autoimmune Encephalitis on 3D Multi-Sequence MRI.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Autoimmune encephalitis (AE) is a noninfectious emergency with severe clinical attacks. It is difficult for the earlier diagnosis of acute AE due to the lack of antibody detection resources.

Neonatal brain inflammation enhances methamphetamine-induced reinstated behavioral sensitization in adult rats analyzed with explainable machine learning.

Neurochemistry international
Neonatal brain inflammation produced by intraperitoneal (i.p.) injection of lipopolysaccharide (LPS) results in long-lasting brain dopaminergic injury and motor disturbances in adult rats. The goal of the present work is to investigate the effect of ...

Interpretable machine learning model for predicting the prognosis of antibody positive autoimmune encephalitis patients.

Journal of affective disorders
OBJECTIVE: The objective was to utilize nine machine learning (ML) methods to predict the prognosis of antibody positive autoimmune encephalitis (AE) patients.

Machine learning for the early prediction of long-term cognitive outcome in autoimmune encephalitis.

Journal of psychosomatic research
BACKGROUND AND OBJECTIVE: Autoimmune encephalitis (AE) is an immune-mediated disease. Some patients experience persistent cognitive deficits despite receiving immunotherapy. We aimed to develop a prediction model for long-term cognitive outcomes in p...

Detection of antibodies in suspected autoimmune encephalitis diseases using machine learning.

Scientific reports
In our study, we aim to predict the antibody serostatus of patients with suspected autoimmune encephalitis (AE) using machine learning based on pre-contrast T2-weighted MR images acquired at symptom onset. A confirmation of seropositivity is of great...