AIMC Topic: Hashimoto Disease

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Machine learning and multi-omics integration identifies immunological predictors and mechanistic insights in autoimmune encephalitis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
OBJECTIVE: To develop an interpretable prognostic prediction model for autoimmune encephalitis (AE) using immunological indicators and to investigate the potential role of nucleophosmin (NPM1) in disease pathogenesis through multi-omics approaches.

Nonenhanced CT-Based radiomics model enhances PTC detection in Hashimoto's thyroiditis.

BMC cancer
BACKGROUND: Hashimoto's thyroiditis (HT) is a common benign thyroid disease that often coexists with papillary thyroid carcinoma (PTC). Owing to the diffuse changes in the thyroid caused by HT, PTCs can be challenging to detect using conventional ima...

Prediction of Seronegative Hashimoto's thyroiditis using machine learning models based on ultrasound radiomics: a multicenter study.

BMC immunology
BACKGROUND: Seronegative Hashimoto's thyroiditis is often underdiagnosed due to the lack of antibody markers. Combining ultrasound radiomics with machine learning offers potential for early detection in patients with normal thyroid function.

Detection of antibodies in suspected autoimmune encephalitis diseases using machine learning.

Scientific reports
In our study, we aim to predict the antibody serostatus of patients with suspected autoimmune encephalitis (AE) using machine learning based on pre-contrast T2-weighted MR images acquired at symptom onset. A confirmation of seropositivity is of great...

Machine learning in lymphocyte and immune biomarker analysis for childhood thyroid diseases in China.

BMC pediatrics
OBJECTIVE: This study aims to characterize and analyze the expression of representative biomarkers like lymphocytes and immune subsets in children with thyroid disorders. It also intends to develop and evaluate a machine learning model to predict if ...

A multicenter diagnostic study of thyroid nodule with Hashimoto's thyroiditis enabled by Hashimoto's thyroiditis nodule-artificial intelligence model.

European radiology
OBJECTIVE: This study aimed to develop a Hashimoto's thyroiditis nodule-artificial intelligence (HTN-AI) model to optimize the diagnosis of thyroid nodules with Hashimoto's thyroiditis (HT) of which the efficiency and accuracy remain challenging.

Machine learning for the early prediction of long-term cognitive outcome in autoimmune encephalitis.

Journal of psychosomatic research
BACKGROUND AND OBJECTIVE: Autoimmune encephalitis (AE) is an immune-mediated disease. Some patients experience persistent cognitive deficits despite receiving immunotherapy. We aimed to develop a prediction model for long-term cognitive outcomes in p...

Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto's thyroiditis.

Scientific reports
While ultrasonography effectively diagnoses Hashimoto's thyroiditis (HT), exploring its transcriptomic landscape could reveal valuable insights into disease mechanisms. This study aimed to identify HT-associated RNA signatures and investigate their p...

Interpretable machine learning model for predicting the prognosis of antibody positive autoimmune encephalitis patients.

Journal of affective disorders
OBJECTIVE: The objective was to utilize nine machine learning (ML) methods to predict the prognosis of antibody positive autoimmune encephalitis (AE) patients.