Understanding epigenetic processes holds immense promise for medical applications. Advances in Machine Learning (ML) are critical to realize this promise. Previous studies used epigenetic data sets associated with the germline transmission of epigene...
BACKGROUND: Lung adenocarcinoma is one of most threatening disease to human health. Although many efforts have been devoted to its genetic study, few researches have been focused on the transcription factors which regulate tumor initiation and progre...
T cell anergy is one of the important mechanisms for immune tolerance. The results of many studies investigating the mechanism for T cell anergy induction have revealed that the expression of several genes was up-regulated in anergic T cells. It has ...
Epigenetic factors are known to correlate with gene expression in the existing studies. However, quantitative models that accurately classify the highly and lowly expressed genes based on epigenetic factors are currently lacking. In this study, a new...
Regeneration is a common phenomenon across multiple animal phyla. Regeneration-related genes (REGs) are critical for fundamental cellular processes such as proliferation and differentiation. Identification of REGs and elucidating their functions may ...
Alu elements are the most abundant retrotransposons in the human genome with more than one million copies. Alu repeats have been reported to participate in multiple processes related with genome regulation and compartmentalization. Moreover, they hav...
Genomic imprinting is an epigenetic occurrence that results in the expression of alleles specific to the parent of origin, plays pivotal roles in plant development, stress adaptation, and agronomic trait regulation. While imprinting has been intensiv...
Epstein-Barr Virus (EBV) is the first tumor virus discovered in humans, which is closely related to the occurrence of a variety of malignant tumors, especially Nasopharyngeal Carcinoma (NPC). Epstein-Barr Virus (EBV)-associated NPC accounts for appro...
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