In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Can...
Journal of neuroengineering and rehabilitation
Feb 5, 2020
BACKGROUND: Arm weight compensation with rehabilitation robots for stroke patients has been successfully used to increase the active range of motion and reduce the effects of pathological muscle synergies. However, the differences in structure, perfo...
OBJECTIVE: Non-invasive fetal electrocardiography has the potential to provide vital information for evaluating the health status of the fetus. However, the low signal-to-noise ratio of the fetal electrocardiogram (ECG) impedes the applicability of t...
BACKGROUND: Behçet's disease (BD) is a chronic multi-systemic vasculitis with a considerable prevalence in Asian countries. There are many genes associated with a higher risk of developing BD, one of which is endoplasmic reticulum aminopeptidase-1 (E...
The use of rolling averages to analyse training data has been debated recently. We evaluated two training load quantification methods (five-zone, seven-zone) fitted to performances over two race distances (50 and 100 m) using four separate longitudin...
European journal of preventive cardiology
Feb 4, 2020
AIMS: Familial hypercholesterolemia (FH) is the most common genetic disorder of lipid metabolism. The gold standard for FH diagnosis is genetic testing, available, however, only in selected university hospitals. Clinical scores - for example, the Dut...
PURPOSE: The purpose of this study was to develop predictive models to classify osteoporosis, osteopenia and normal patients using radiomics and machine learning approaches.
International journal of medical informatics
Feb 4, 2020
INTRODUCTION: Research has shown that frailty, a geriatric syndrome associated with an increased risk of negative outcomes for older people, is highly prevalent among residents of residential aged care facilities (also called long term care facilitie...
BACKGROUND AND PURPOSE: Multiparametric radiological imaging is vital for detection, characterization, and diagnosis of many different diseases. Radiomics provide quantitative metrics from radiological imaging that may infer potential biological mean...
Background A multitask deep learning model might be useful in large epidemiologic studies wherein detailed structural assessment of osteoarthritis still relies on expert radiologists' readings. The potential of such a model in clinical routine should...
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