BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of preventable morbidity and mortality, highlighting the need for early risk stratification in primary prevention. Traditional Cox models assume proportional hazards and linear effects,...
An April 2025 survey of 118 first-year Japanese medical students found high use of generative artificial intelligence (84.7%) but limited formal learning (49.2%), with strong learning interest yet neutral assignment use, indicating a need for structu...
Chronic spontaneous urticaria (CSU) is an autoimmune prompted skin disorder, whose hallmarks include the unpredictable onset of hives and itch. Symptom duration typically exceed 6 weeks, and flares can occur for up to 5 years or longer if untreated, ...
BACKGROUND: Vacuum-assisted breast biopsy (VABB) is a widely adopted minimally invasive technique for the diagnosis and treatment of breast lesions. However, the procedure heavily relies on real-time ultrasound guidance, posing significant challenges...
Biofeedback-based treadmill training generally involves 10 or more sessions to assess its effectiveness during stroke rehabilitation. Improvements are seen in some patients during the assessment, while others do not progress. Our aim in this study is...
BACKGROUND: Risk of coronary heart disease (CHD) in a specific period of years can be assessed using scores calculated by models, such as pooled cohort equations (PCEs) and Framingham Risk Score. However, there are few studies on on-site estimation o...
BACKGROUND: Hashimoto's thyroiditis (HT) is a common benign thyroid disease that often coexists with papillary thyroid carcinoma (PTC). Owing to the diffuse changes in the thyroid caused by HT, PTCs can be challenging to detect using conventional ima...
A high-accuracy DNA-based cancer risk predictor was developed by blending Logistic Regression with Gaussian Naive Bayes, and its hyperparameters were optimized via grid search. Five cancer types (BRCA1, KIRC, COAD, LUAD, PRAD) were classified in a co...
Crossmodal interactions involve crosstalk between different cortical areas and dynamic recruitment of regions, which is crucial for integrating sensory information into a coherent percept. Despite their significance, the dynamic cortical networks und...
BACKGROUND: KMT2B-related dystonia is a childhood-onset movement disorder. This study investigated a novel KMT2B gene variant using whole exome sequencing (WES) and bioinformatics analysis, and expanded the known clinical spectrum of KMT2B-related dy...
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