AIMC Topic: Glomerulonephritis, Membranous

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Rapid diagnosis of membranous nephropathy based on serum and urine Raman spectroscopy combined with deep learning methods.

Scientific reports
Membranous nephropathy is the main cause of nephrotic syndrome, which has an insidious onset and may progress to end-stage renal disease with a high mortality rate, such as renal failure and uremia. At present, the diagnosis of membranous nephropathy...

Explainable Biomarkers for Automated Glomerular and Patient-Level Disease Classification.

Kidney360
Pathologists use multiple microscopy modalities to assess renal biopsy specimens. Besides usual diagnostic features, some changes are too subtle to be properly defined. Computational approaches have the potential to systematically quantitate subvisua...

Deep learning-based framework for the distinction of membranous nephropathy: a new approach through hyperspectral imagery.

BMC nephrology
BACKGROUND: Common subtypes seen in Chinese patients with membranous nephropathy (MN) include idiopathic membranous nephropathy (IMN) and hepatitis B virus-related membranous nephropathy (HBV-MN). However, the morphologic differences are not visible ...

Identification of novel therapeutic targets in hepatitis-B virus-associated membranous nephropathy using scRNA-seq and machine learning.

Scientific reports
Hepatitis B Virus-associated membranous nephropathy (HBV-MN) significantly impacts renal health, particularly in areas with high HBV prevalence. Understanding the molecular mechanisms underlying HBV-MN is crucial for developing effective therapeutic ...