Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
38599040
Glomerulus morphology on renal pathology images provides valuable diagnosis and outcome prediction information. To provide better care, an efficient, standardized, and scalable method is urgently needed to optimize the time-consuming and labor-intens...
BACKGROUND: Glomerular lesions are the main injuries of diabetic nephropathy (DN) and are used as a crucial index for pathologic classification. Manual quantification of these morphologic features currently used is semi-quantitative and time-consumin...
Computer methods and programs in biomedicine
38964248
BACKGROUND AND OBJECTIVE: In renal disease research, precise glomerular disease diagnosis is crucial for treatment and prognosis. Currently reliant on invasive biopsies, this method bears risks and pathologist-dependent variability, yielding inconsis...
International journal of computer assisted radiology and surgery
38848032
PURPOSE: In pathology images, different stains highlight different glomerular structures, so a supervised deep learning-based glomerular instance segmentation model trained on individual stains performs poorly on other stains. However, it is difficul...
Journal of the American Society of Nephrology : JASN
40029749
BACKGROUND: Deep learning has great potential in digital kidney pathology. However, its effectiveness depends heavily on the availability of extensively labeled datasets, which are often limited because of the specialized knowledge and time required ...
OBJECTIVE: Recognizing glomerular lesions is essential in diagnosing chronic kidney disease. However, deep learning faces challenges due to the lesion heterogeneity, superposition, progression, and tissue incompleteness, leading to uncertainty in mod...
To decrease the number of chronic kidney disease (CKD), early diagnosis of diabetic kidney disease is required. We performed invariant information clustering (IIC)-based clustering on glomerular images obtained from nephrectomized kidneys of patients...
Accurate segmentation and classification of glomeruli are fundamental to histopathology slide analysis in renal pathology, which helps to characterize individual kidney disease. Accurate segmentation of glomeruli of different types faces two main cha...
Acute allograft rejection in patients undergoing renal transplantation is diagnosed through histopathological analysis of renal graft biopsies, which can be used to quantify elementary lesions. However, quantification of elementary lesions requires c...
Diabetes mellitus (DM) is a chronic metabolic disorder that poses significant challenges to public health. Among its various complications, diabetic nephropathy (DN) emerges as a critical microvascular complication associated with high mortality rate...