AIMC Topic: Hepatitis B

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Construction and validation of HBV-ACLF bacterial infection diagnosis model based on machine learning.

BMC infectious diseases
OBJECTIVE: To develop and validate a novel diagnostic model for detecting bacterial infections in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) using advanced machine learning algorithms. The focus is on improving ...

Anti-HBs persistence and anamnestic response among medical interns vaccinated in infancy.

Scientific reports
Medical interns are at high risk of acquiring Hepatitis B Virus (HBV) infection during their training. HBV vaccination is the most effective measure to reduce the global incidence of HBV. The duration of protection after HBV vaccination is still cont...

Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.

Frontiers in immunology
BACKGROUND: Immune checkpoint inhibitors have proven efficacy against hepatitis B-virus positive hepatocellular. However, Immunotherapy-related adverse reactions are still a major challenge faced by tumor immunotherapy, so it is urgent to establish n...

A multi-layer neural network approach for the stability analysis of the Hepatitis B model.

Computational biology and chemistry
In the present study, we explore the dynamics of Hepatitis B virus infection, a significant global health issue, through a newly developed dynamics system. This model is distinguished by its inclusion of asymptomatic carriers and the impact of vaccin...

Predictive modeling of hepatitis B viral dynamics: a caputo derivative-based approach using artificial neural networks.

Scientific reports
A fractional model for the kinetics of hepatitis B transmission was developed. The hepatitis B virus significantly affects the world's economic and health systems. Acute and chronic carrier phases play a crucial part in the spread of the HBV infectio...

Advanced Prediction of Hepatic Oncogenic Transformation in HBV Patients via RNA-Seq Data Analysis and Deep Learning Techniques.

International journal of molecular sciences
Liver cancer, recognized as a significant global health issue, is increasingly correlated with Hepatitis B virus (HBV) infection, as evidenced by numerous scientific studies. This study aims to examine the correlation between HBV infection and the de...

Integrating bioinformatics and machine learning methods to analyze diagnostic biomarkers for HBV-induced hepatocellular carcinoma.

Diagnostic pathology
Hepatocellular carcinoma (HCC) is a malignant tumor. It is estimated that approximately 50-80% of HCC cases worldwide are caused by hepatitis b virus (HBV) infection, and other pathogenic factors have been shown to promote the development of HCC when...

Neural Network Enables High Accuracy for Hepatitis B Surface Antigen Detection with a Plasmonic Platform.

Nano letters
The detection of hepatitis B surface antigen (HBsAg) is critical in diagnosing hepatitis B virus (HBV) infection. However, existing clinical detection technologies inevitably cause certain inaccuracies, leading to delayed or unwarranted treatment. He...

Machine learning-based model for predicting tumor recurrence after interventional therapy in HBV-related hepatocellular carcinoma patients with low preoperative platelet-albumin-bilirubin score.

Frontiers in immunology
INTRODUCTION: This study aimed to develop a prognostic nomogram for predicting the recurrence-free survival (RFS) of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients with low preoperative platelet-albumin-bilirubin (PALBI) scor...