AIMC Topic: Healthy Aging
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Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging.
Neurobiology of aging
Mar 6, 2020
Numerous studies have established that estimated brain age constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In this work, we curate a large-scale brain MRI data set of healthy individuals, on...
The NAD-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications.
Mechanisms of ageing and development
Dec 5, 2019
Nicotinamide adenine dinucleotide (NAD) is an important natural molecule involved in fundamental biological processes, including the TCA cycle, OXPHOS, β-oxidation, and is a co-factor for proteins promoting healthy longevity. NAD depletion is associa...
Robots and people with dementia: Unintended consequences and moral hazard.
Nursing ethics
Dec 20, 2017
The use of social robots in elder care is entering the mainstream as robots become more sophisticated and populations age. While there are many potential benefits to the use of social robots in care for the older people, there are ethical challenges ...
Advanced analytical methodologies for measuring healthy ageing and its determinants, using factor analysis and machine learning techniques: the ATHLOS project.
Scientific reports
Mar 10, 2017
A most challenging task for scientists that are involved in the study of ageing is the development of a measure to quantify health status across populations and over time. In the present study, a Bayesian multilevel Item Response Theory approach is u...
Exploring the complex associations between community public spaces and healthy aging: an explainable analysis using catboost and SHAP.
BMC public health
Jul 2, 2025
BACKGROUND: As global aging accelerates, community public spaces (CPS) are increasingly recognized as vital for promoting healthy aging. However, existing research often employs linear analytical methods or focuses on single health dimensions, overlo...
Biomarker signatures associated with ageing free of major chronic diseases: results from a population-based sample of the EPIC-Potsdam cohort.
Age and ageing
May 11, 2024
BACKGROUND: A number of biomarkers denoting various pathophysiological pathways have been implicated in the aetiology and risk of age-related diseases. Hence, the combined impact of multiple biomarkers in relation to ageing free of major chronic dise...
Promoting Healthy Aging Using a Robot Support System and Emotion Recognition.
Studies in health technology and informatics
May 2, 2023
The aging population poses challenges such as loneliness, decreased mobility, and medical conditions. To tackle these issues, a proposed robot platform offers personalized well-being behavior change suggestions. Developed through a user-centered proc...
Living Longer Better.
Plastic and reconstructive surgery
Dec 1, 2021
Aging is a universal feature of life and a complex process at all levels from the biological to the societal. What constitutes older age is subjective and flexible, and how one defines older age is influenced by everchanging individual, generational,...
Short-Term Memory Binding Distinguishing Amnestic Mild Cognitive Impairment from Healthy Aging: A Machine Learning Study.
Journal of Alzheimer's disease : JAD
Jan 1, 2021
BACKGROUND: Amnestic mild cognitive impairment (aMCI) is the most common preclinical stage of Alzheimer's disease (AD). A strategy to reduce the impact of AD is the early aMCI diagnosis and clinical intervention. Neuroimaging, neurobiological, and ge...
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