AIMC Topic: Healthy Aging

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Deep learning of resting-state electroencephalogram signals for three-class classification of Alzheimer's disease, mild cognitive impairment and healthy ageing.

Journal of neural engineering
This study aimed to produce a novel deep learning (DL) model for the classification of subjects with Alzheimer's disease (AD), mild cognitive impairment (MCI) subjects and healthy ageing (HA) subjects using resting-state scalp electroencephalogram (E...

Internet of Things and Machine Learning for Healthy Ageing: Identifying the Early Signs of Dementia.

Sensors (Basel, Switzerland)
Identifying the symptoms of the early stages of dementia is a difficult task, particularly for older adults living in residential care. Internet of Things (IoT) and smart environments can assist with the early detection of dementia, by nonintrusive m...

Alzheimer's disease, mild cognitive impairment, and normal aging distinguished by multi-modal parcellation and machine learning.

Scientific reports
A 360-area surface-based cortical parcellation is extended to study mild cognitive impairment (MCI) and Alzheimer's disease (AD) from healthy control (HC) using the joint human connectome project multi-modal parcellation (JHCPMMP) proposed by us. We ...

Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging.

Neurobiology of aging
Numerous studies have established that estimated brain age constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In this work, we curate a large-scale brain MRI data set of healthy individuals, on...

The NAD-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications.

Mechanisms of ageing and development
Nicotinamide adenine dinucleotide (NAD) is an important natural molecule involved in fundamental biological processes, including the TCA cycle, OXPHOS, β-oxidation, and is a co-factor for proteins promoting healthy longevity. NAD depletion is associa...

Robots and people with dementia: Unintended consequences and moral hazard.

Nursing ethics
The use of social robots in elder care is entering the mainstream as robots become more sophisticated and populations age. While there are many potential benefits to the use of social robots in care for the older people, there are ethical challenges ...

Advanced analytical methodologies for measuring healthy ageing and its determinants, using factor analysis and machine learning techniques: the ATHLOS project.

Scientific reports
A most challenging task for scientists that are involved in the study of ageing is the development of a measure to quantify health status across populations and over time. In the present study, a Bayesian multilevel Item Response Theory approach is u...

Biomarker signatures associated with ageing free of major chronic diseases: results from a population-based sample of the EPIC-Potsdam cohort.

Age and ageing
BACKGROUND: A number of biomarkers denoting various pathophysiological pathways have been implicated in the aetiology and risk of age-related diseases. Hence, the combined impact of multiple biomarkers in relation to ageing free of major chronic dise...

Promoting Healthy Aging Using a Robot Support System and Emotion Recognition.

Studies in health technology and informatics
The aging population poses challenges such as loneliness, decreased mobility, and medical conditions. To tackle these issues, a proposed robot platform offers personalized well-being behavior change suggestions. Developed through a user-centered proc...