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Heart Failure

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Time-frequency time-space long short-term memory networks for image classification of histopathological tissue.

Scientific reports
Image analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultim...

Decoding empagliflozin's molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence.

Scientific reports
The use of sodium-glucose co-transporter 2 inhibitors to treat heart failure with preserved ejection fraction (HFpEF) is under investigation in ongoing clinical trials, but the exact mechanism of action is unclear. Here we aimed to use artificial int...

Machine ​learning algorithms for claims data-based prediction of in-hospital mortality in patients with heart failure.

ESC heart failure
AIMS: Models predicting mortality in heart failure (HF) patients are often limited with regard to performance and applicability. The aim of this study was to develop a reliable algorithm to compute expected in-hospital mortality rates in HF cohorts o...

A Machine Learning Approach to the Interpretation of Cardiopulmonary Exercise Tests: Development and Validation.

Pulmonary medicine
OBJECTIVE: At present, there is no consensus on the best strategy for interpreting the cardiopulmonary exercise test's (CPET) results. This study is aimed at assessing the potential of using computer-aided algorithms to evaluate CPET data for identif...

Deep-Learning Models for the Echocardiographic Assessment of Diastolic Dysfunction.

JACC. Cardiovascular imaging
OBJECTIVES: The authors explored a deep neural network (DeepNN) model that integrates multidimensional echocardiographic data to identify distinct patient subgroups with heart failure with preserved ejection fraction (HFpEF).

A machine learning model for identifying patients at risk for wild-type transthyretin amyloid cardiomyopathy.

Nature communications
Transthyretin amyloid cardiomyopathy, an often unrecognized cause of heart failure, is now treatable with a transthyretin stabilizer. It is therefore important to identify at-risk patients who can undergo targeted testing for earlier diagnosis and tr...

The Comprehensive Machine Learning Analytics for Heart Failure.

International journal of environmental research and public health
: Early detection of heart failure is the basis for better medical treatment and prognosis. Over the last decades, both prevalence and incidence rates of heart failure have increased worldwide, resulting in a significant global public health issue. H...

Artificial intelligence-enabled electrocardiograms for identification of patients with low ejection fraction: a pragmatic, randomized clinical trial.

Nature medicine
We have conducted a pragmatic clinical trial aimed to assess whether an electrocardiogram (ECG)-based, artificial intelligence (AI)-powered clinical decision support tool enables early diagnosis of low ejection fraction (EF), a condition that is unde...

Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis.

Circulation
BACKGROUND: Heart failure (HF) risk and the underlying risk factors vary by race. Traditional models for HF risk prediction treat race as a covariate in risk prediction and do not account for significant parameters such as cardiac biomarkers. Machine...