AIMC Topic: Human Growth Hormone

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Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.

Endocrine Dec 22, 2017
PURPOSE: Growth hormone (GH) therapy in adults alters thyroid function, and acromegaly often involves thyroid disease. The present study aimed to elucidate roles and mechanisms of GH in regulating thyroid function.
Triiodothyronine Male Gene Expression Regulation Middle Aged Acromegaly Thyroid Gland Cell Line Human Growth Hormone Thyroxine Hormone Replacement Therapy Female Dwarfism, Pituitary Young Adult Humans Iodide Peroxidase Adult Retrospective Studies Iodothyronine Deiodinase Type II
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Effects of gender, body weight, and blood glucose dynamics on the growth hormone response to the glucagon stimulation test in patients with pituitary disease.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society Dec 8, 2015
OBJECTIVE: Body weight blunts the growth hormone (GH) response to provocative stimuli. The appropriate GH cut-off to confirm GH deficiency in obese and overweight patients undergoing the glucagon stimulation test (GST) has recently been questioned. W...
Adolescent Human Growth Hormone Blood Glucose Body Weight Sex Factors Adult Male Middle Aged Aged Young Adult Humans Pituitary Diseases Diagnostic Techniques, Endocrine Retrospective Studies Glucagon Female
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Machine Learning-based Prediction Model for Treatment of Acromegaly With First-generation Somatostatin Receptor Ligands.

The Journal of clinical endocrinology and metabolism Jun 16, 2021
CONTEXT: Artificial intelligence (AI), in particular machine learning (ML), may be used to deeply analyze biomarkers of response to first-generation somatostatin receptor ligands (fg-SRLs) in the treatment of acromegaly.
Logistic Models Treatment Outcome Predictive Value of Tests Human Growth Hormone Aged Keratins Machine Learning Insulin-Like Growth Factor I Young Adult Drug Monitoring Clinical Decision Rules Biomarkers Adult Ligands Receptors, Somatostatin Female Humans Male Acromegaly Middle Aged
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Using Deep Learning for Individual-Level Predictions of Adherence with Growth Hormone Therapy.

Studies in health technology and informatics May 27, 2021
The problem of consistent therapy adherence is a current challenge for health informatics, and its solution can increase the success rate of treatments. Here we show a methodology to predict, at individual-level, future therapy adherence for patients...
Deep Learning Human Growth Hormone Patient Compliance Humans Neural Networks, Computer Growth Hormone
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Machine learning-based prediction of response to growth hormone treatment in Turner syndrome: the LG Growth Study.

Journal of pediatric endocrinology & metabolism : JPEM Jan 28, 2020
Background Growth hormone (GH) treatment has become a common practice in Turner syndrome (TS). However, there are only a few studies on the response to GH treatment in TS. The aim of this study is to predict the responsiveness to GH treatment and to ...
Child Predictive Value of Tests Body Height Time Factors Growth Disorders Turner Syndrome Machine Learning Retrospective Studies Female Male Human Growth Hormone Humans
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Neural network models - a novel tool for predicting the efficacy of growth hormone (GH) therapy in children with short stature.

Neuro endocrinology letters Jan 1, 2015
INTRODUCTION: The leading method for prediction of growth hormone (GH) therapy effectiveness are multiple linear regression (MLR) models. Best of our knowledge, we are the first to apply artificial neural networks (ANN) to solve this problem. For ANN...
Dwarfism Growth Hormone Outcome Assessment, Health Care Body Height Female Male Adolescent Humans Human Growth Hormone Neural Networks, Computer Child Recombinant Proteins
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