OBJECTIVE: Interstitial lung disease (ILD) represents the most common and severe organ manifestation observed in patients diagnosed with connective tissue diseases (CTDs). The aim of this retrospective cross-sectional study was to identify clinical r...
BACKGROUND: Patients' protection motivation (PM) and self-care behaviors are essential for sustaining oral hygiene adherence and long-term periodontal health.
BACKGROUND: Severe tubular atrophy/interstitial fibrosis are critical pathological features associated with poor prognosis in IgA nephropathy (IgAN). The early identification of patients at high risk for severe tubular damage could guide clinical man...
Despite the current ubiquity of large language models (LLMs) across the medical domain, there is a surprising lack of studies which address their . We emphasise the importance of understanding as opposed to high-level prediction accuracies, since it...
BACKGROUND: Sleep insufficiency, driven by modern fast-paced lifestyles, contributes to the accumulation of "sleep debt." Many individuals attempt to compensate through weekend catch-up sleep (WCS). While WCS may temporarily relieve fatigue and enhan...
Environmental geochemistry and health
Oct 28, 2025
High-altitude ecosystems face growing threats from natural hazards and human activities, intensifying socio-economic and environmental risks. The Nilgiris District, Tamil Nadu, is a hotspot where steep terrain, fragile ecosystems, climate variability...
BACKGROUND: Cytosine modifications play critical roles in gene regulation and disease pathogenesis. Elucidating novel epigenetic contributions to Alzheimer's disease (AD) could advance diagnostic, prognostic, and therapeutic strategies. 5-hydroxymeth...
BACKGROUND: Adolescence marks a critical period for the onset of anxiety disorders, yet they frequently remain undiagnosed due to barriers such as reluctance to self-disclose symptoms. Objective screening methods that bypass self-report may improve e...
Journal of computer-aided molecular design
Oct 28, 2025
Drug repositioning (DR) is a highly promising research strategy aimed at discovering new therapeutic indications for existing drugs. Current computational DR methods have become effective tools for uncovering drug-disease associations, yet they suffe...
Metal implants and other high-density objects cause significant artifacts in computed tomography (CT) images, hindering clinical diagnosis. Traditional metal artifact reduction methods often leave residual artifacts due to sinogram edges discontinuit...
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