AIMC Topic: Humans
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Development of an interpretable machine learning model for frailty risk prediction in older adult care institutions: a mixed-methods, cross-sectional study in China.
BMJ open
Jul 5, 2025
OBJECTIVE: To develop and validate an interpretable machine learning (ML)-based frailty risk prediction model that combines real-time health data with validated scale assessments for enhanced decision-making and targeted health management in integrat...
Research on transcranial magnetic stimulation for stroke rehabilitation: a visual analysis based on CiteSpace.
European journal of medical research
Jul 5, 2025
OBJECTIVE: This study aimed to analyze recent research and emerging trends in transcranial magnetic stimulation (TMS) for stroke rehabilitation.
Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.
Journal of nanobiotechnology
Jul 5, 2025
BACKGROUND: Osteoarthritis (OA), the most prevalent joint disorder, is characterized by a complex etiology and a lack of safe and effective therapeutic interventions. Emerging evidence suggests that immune cell dysregulation plays a pivotal role in t...
Diabetic retinopathy in rural communities: a review of barriers to access of care and potential solutions.
Annals of medicine
Jul 4, 2025
INTRODUCTION: Diabetic retinopathy (DR) is a leading cause of vision loss. With an estimated 38.4 million Americans diagnosed with DM, the disease exerts a significant burden on healthcare systems, especially in rural areas where access to care is li...
Combination of machine learning and protein‑protein interaction network established one ATM‑DPP4‑TXN ferroptotic diagnostic model with experimental validation.
Molecular medicine reports
Jul 4, 2025
Ferroptosis and lethal sepsis are interlinked, although this association remains largely unknown to clinical panels. Sepsis is characterized by dysfunction of the inflammatory microenvironment. Most septic biomarkers lack independent validation, and ...
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer's disease in cerebrospinal fluid.
Alzheimer's research & therapy
Jul 4, 2025
BACKGROUND: The complex pathogenesis of Alzheimer's disease (AD) has resulted in limited current biomarkers for its classification and diagnosis, necessitating further investigation into reliable universal biomarkers or combinations.
Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data.
Biology direct
Jul 4, 2025
BACKGROUND: Oxidative stress plays a crucial role in the development of diabetic foot ulcers (DFU). However, its underlying mechanisms are not fully understood. The purpose of this study was to use bioinformatics and preliminary validation methods to...
Effects of device-assisted practice of activities of daily living in a close-to-normal pattern on upper extremity motor recovery in individuals with moderate to severe stroke: study protocol of a randomized control trial.
Trials
Jul 4, 2025
BACKGROUND: The majority of individuals with chronic stroke have residual upper extremity (UE) disability which they cite as their greatest barrier to recovery. Using orthoses, robotic devices, and functional electrical stimulation (FES) represent re...
Severity of Illness Index
Time Factors
Treatment Outcome
Recovery of Function
Humans
Research Design
Paresis
Motor Activity
Upper Extremity
Clinical Protocols
Electric Stimulation Therapy
Stroke Rehabilitation
Equipment Design
Robotics
Stroke
Disability Evaluation
Activities of Daily Living
Double-Blind Method
Orthotic Devices
Machine learning-based predictive tools and nomogram for in-hospital mortality in critically ill cancer patients: development and external validation using retrospective cohorts.
BMC medical informatics and decision making
Jul 4, 2025
BACKGROUND: The incidence of intensive care unit (ICU) admissions and the corresponding mortality rates among cancer patients are both high. However, the existing scoring systems all lack specificity. This research seeks to establish and validate a p...
Predicting Quality of Life in People Living with HIV: A Machine Learning Model Integrating Multidimensional Determinants.
Health and quality of life outcomes
Jul 4, 2025
OBJECTIVE: With survival steadily improving among people living with HIV(PLWH), quality of life (QoL) has emerged as the ultimate benchmark of therapeutic success. We therefore aimed to develop and validate machine learning models that predict QoL tr...
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