AIMC Topic: Humans

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Experimental drugs in clinical trials for COPD: artificial intelligence via machine learning approach to predict the successful advance from early-stage development to approval.

Expert opinion on investigational drugs
INTRODUCTION: Therapeutic advances in drug therapy of chronic obstructive pulmonary disease (COPD) really effective in suppressing the pathological processes underlying the disease deterioration are still needed. Artificial Intelligence (AI) via Mach...

Exploring the potential of Chat-GPT as a supportive tool for sialendoscopy clinical decision making and patient information support.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
INTRODUCTION: Sialendoscopy has emerged in the last decades as a groundbreaking technique, offering a minimally invasive approach for exploring and managing salivary gland disorders. More recently, the advent of chatbots, powered by advanced natural ...

A Channel-Dimensional Feature-Reconstructed Deep Learning Model for Predicting Breast Cancer Molecular Subtypes on Overall b-Value Diffusion-Weighted MRI.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Dynamic contrast-enhanced (DCE) MRI commonly outperforms diffusion-weighted (DW) MRI in breast cancer discrimination. However, the side effects of contrast agents limit the use of DCE-MRI, particularly in patients with chronic kidney dise...

A hierarchical self-attention-guided deep learning framework to predict breast cancer response to chemotherapy using pre-treatment tumor biopsies.

Medical physics
BACKGROUND: Pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) has demonstrated a strong correlation to improved survival in breast cancer (BC) patients. However, pCR rates to NAC are less than 30%, depending on the BC subtype. Ea...

Predicting GPR40 Agonists with A Deep Learning-Based Ensemble Model.

ChemistryOpen
Recent studies have identified G protein-coupled receptor 40 (GPR40) as a promising target for treating type 2 diabetes mellitus, and GPR40 agonists have several superior effects over other hypoglycemic drugs, including cardiovascular protection and ...

Identifying inpatient mortality in MarketScan claims data using machine learning.

Pharmacoepidemiology and drug safety
PURPOSE: Inpatient mortality is an important variable in epidemiology studies using claims data. In 2016, MarketScan data began obscuring specific hospital discharge status types for patient privacy, including inpatient deaths, by setting the values ...

BayeSeg: Bayesian modeling for medical image segmentation with interpretable generalizability.

Medical image analysis
Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the benefits of...

PL-TARMI: A deep learning framework for pixel-level traffic crash risk map inference.

Accident; analysis and prevention
A citywide traffic crash risk map is of great significance for preventing future traffic crashes. However, the fine-grained geographic traffic crash risk inference is still a challenging task, mainly due to the complex road network structure, human b...

Deep Learning-Based Skin Lesion Multi-class Classification with Global Average Pooling Improvement.

Journal of digital imaging
Cancerous skin lesions are one of the deadliest diseases that have the ability in spreading across other body parts and organs. Conventionally, visual inspection and biopsy methods are widely used to detect skin cancers. However, these methods have s...