AIMC Topic: Humans

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Point-of-need one-pot multiplexed RT-LAMP test for detecting three common respiratory viruses in saliva.

Biosensors & bioelectronics
Respiratory viral infections pose a significant global public health challenge, partly due to the difficulty in rapidly and accurately distinguishing between viruses with similar symptoms at the point of care, hindering timely and appropriate treatme...

Evaluation, correction and masking methods for unpleasant tastes of drugs: A comprehensive review.

International journal of pharmaceutics
The unpleasant tastes of drugs, including bitterness, pungency, astringency, and sourness, significantly impedes patient adherence, particularly among pediatric and geriatric populations. Accurate evaluation of these tastes is essential for optimizin...

Toroidal indentation for measuring cell and tissue mechanical anisotropy.

Acta biomaterialia
Indentation-based mechanical tests are advantageous for measuring tissue and cell stiffness due to their simplicity and ability to probe samples non-destructively. Most commonly, spherical or pyramidal probes are used, and Hertzian analysis is applie...

Ultrasound-based machine learning models for predicting response to neoadjuvant chemotherapy in breast cancer: A meta-analysis.

Clinical imaging
BACKGROUND AND AIMS: Breast cancer remains the most common cancer among women globally, with neoadjuvant chemotherapy (NAC) serving as a critical pre-surgical intervention. Ultrasound-based radiomics and machine learning (ML) models offer potential f...

A beautiful loop: An active inference theory of consciousness.

Neuroscience and biobehavioral reviews
Can active inference model consciousness? We offer three conditions implying that it can. The first condition is the simulation of a world model, which determines what can be known or acted upon; namely an epistemic field. The second is inferential c...

CDE-Mapper: Using retrieval-augmented language models for linking clinical data elements to controlled vocabularies.

Computers in biology and medicine
The standardization of clinical data elements (CDEs) aims to ensure consistent and comprehensive patient information across various healthcare systems. Existing methods often falter when standardizing CDEs of varying representation and complex struct...

Efficacy of image similarity as a metric for augmenting small dataset retinal image segmentation.

Computers in biology and medicine
Synthetic images are an option for augmenting limited medical imaging datasets to improve the performance of various machine learning models. A common metric for evaluating synthetic image quality is the Fréchet Inception Distance (FID) which measure...

M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization.

Computers in biology and medicine
Breast cancer remains a leading cause of morbidity and mortality worldwide. Histopathology, particularly the analysis of nuclear morphology in tissue samples, is critical for diagnosing and understanding the progression of breast cancer. Accurate nuc...

Leveraging weak supervision for cell localization in digital pathology using multitask learning and consistency loss.

Computers in biology and medicine
Cell detection and segmentation are integral parts of automated systems in digital pathology. Encoder-decoder networks have emerged as a promising solution for these tasks. However, training of these networks has typically required full boundary anno...

Interpretable one-class classification framework for prescription error detection using BERT embeddings and dimensionality reduction.

Computers in biology and medicine
Ensuring accurate prescriptions and proper medication administration is critical for patient safety and effective clinical outcomes. Identifying and preventing prescription errors can significantly reduce healthcare costs and adverse health effects. ...