AIMC Topic: Humans

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Prediction of functional outcomes of schizophrenia with genetic biomarkers using a bagging ensemble machine learning method with feature selection.

Scientific reports
Genetic variants such as single nucleotide polymorphisms (SNPs) have been suggested as potential molecular biomarkers to predict the functional outcome of psychiatric disorders. To assess the schizophrenia' functional outcomes such as Quality of Life...

A generative adversarial network-based abnormality detection using only normal images for model training with application to digital breast tomosynthesis.

Scientific reports
Deep learning has shown tremendous potential in the task of object detection in images. However, a common challenge with this task is when only a limited number of images containing the object of interest are available. This is a particular issue in ...

Kernel machine SNP set analysis finds the association of BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran Cardio-metabolic Genetics Study.

Scientific reports
Metabolic syndrome (MetS) is one of the most important risk factors for cardiovascular disease. The 11p23.3 chromosomal region plays a potential role in the pathogenesis of MetS. The present study aimed to assess the association between 18 single nuc...

OASIS +: leveraging machine learning to improve the prognostic accuracy of OASIS severity score for predicting in-hospital mortality.

BMC medical informatics and decision making
BACKGROUND: Severity scores assess the acuity of critical illness by penalizing for the deviation of physiologic measurements from normal and aggregating these penalties (also called "weights" or "subscores") into a final score (or probability) for q...

A review of deep learning based methods for medical image multi-organ segmentation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Deep learning has revolutionized image processing and achieved the-state-of-art performance in many medical image segmentation tasks. Many deep learning-based methods have been published to segment different parts of the body for different medical ap...

Deep learning applied to electroencephalogram data in mental disorders: A systematic review.

Biological psychology
In recent medical research, tremendous progress has been made in the application of deep learning (DL) techniques. This article systematically reviews how DL techniques have been applied to electroencephalogram (EEG) data for diagnostic and predictiv...

Red blood cell phenotyping from 3D confocal images using artificial neural networks.

PLoS computational biology
The investigation of cell shapes mostly relies on the manual classification of 2D images, causing a subjective and time consuming evaluation based on a portion of the cell surface. We present a dual-stage neural network architecture for analyzing fin...

Global importance analysis: An interpretability method to quantify importance of genomic features in deep neural networks.

PLoS computational biology
Deep neural networks have demonstrated improved performance at predicting the sequence specificities of DNA- and RNA-binding proteins compared to previous methods that rely on k-mers and position weight matrices. To gain insights into why a DNN makes...

Current and emerging artificial intelligence applications for pediatric interventional radiology.

Pediatric radiology
Artificial intelligence in medicine can help improve the accuracy and efficiency of diagnostics, selection of therapies and prediction of outcomes. Machine learning describes a subset of artificial intelligence that utilizes algorithms that can learn...

Design publicity of black box algorithms: a support to the epistemic and ethical justifications of medical AI systems.

Journal of medical ethics
In their article 'Who is afraid of black box algorithms? On the epistemological and ethical basis of trust in medical AI', Durán and Jongsma discuss the epistemic and ethical challenges raised by black box algorithms in medical practice. The opacity ...