AIMC Topic: Humans

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Splice sites detection using chaos game representation and neural network.

Genomics
A novel method is proposed to detect the acceptor and donor splice sites using chaos game representation and artificial neural network. In order to achieve high accuracy, inputs to the neural network, or feature vector, shall reflect the true nature ...

Machine Learning of Discriminative Gate Locations for Clinical Diagnosis.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
High-throughput single-cell cytometry technologies have significantly improved our understanding of cellular phenotypes to support translational research and the clinical diagnosis of hematological and immunological diseases. However, subjective and ...

Classification of Human White Blood Cells Using Machine Learning for Stain-Free Imaging Flow Cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Imaging flow cytometry (IFC) produces up to 12 spectrally distinct, information-rich images of single cells at a throughput of 5,000 cells per second. Yet often, cell populations are still studied using manual gating, a technique that has several dra...

A network perspective on body dysmorphic disorder and major depressive disorder.

Journal of affective disorders
BACKGROUND: Body dysmorphic disorder (BDD) is a highly debilitating mental disorder associated with notable psychosocial impairment and high rates of suicidality. This study investigated BDD from a network perspective, which conceptualizes mental dis...

Safety and immediate effects of Hybrid Assistive Limb in children with cerebral palsy: A pilot study.

Brain & development
PURPOSE: Early intervention is effective for developing motor ability and preventing contractures and deformities in patients with cerebral palsy (CP). Gait training using the newly developed Hybrid Assistive Limb (HAL) shows promise as an interventi...

Improved detection of Parkinsonian resting tremor with feature engineering and Kalman filtering.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Accurate and reliable detection of tremor onset in Parkinson's disease (PD) is critical to the success of adaptive deep brain stimulation (aDBS) therapy. Here, we investigated the potential use of feature engineering and machine learning m...

The Clinical Pharmacogenetics Implementation Consortium: 10 Years Later.

Clinical pharmacology and therapeutics
In 2009, the Clinical Pharmacogenetics Implementation Consortium (CPIC, www.cpicpgx.org), a shared project between Pharmacogenomics Knowledge Base (PharmGKB, http://www.pharmgkb.org) and the National Institutes of Health (NIH), was created to provide...

Convolutional neural networks for dental image diagnostics: A scoping review.

Journal of dentistry
OBJECTIVES: Convolutional neural networks (CNNs) are increasingly applied for medical image diagnostics. We performed a scoping review, exploring (1) use cases, (2) methodologies and (3) findings of studies applying CNN on dental image material.