AIMC Topic: Humans

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DeepNEU: cellular reprogramming comes of age - a machine learning platform with application to rare diseases research.

Orphanet journal of rare diseases
BACKGROUND: Conversion of human somatic cells into induced pluripotent stem cells (iPSCs) is often an inefficient, time consuming and expensive process. Also, the tendency of iPSCs to revert to their original somatic cell type over time continues to ...

A classification framework for exploiting sparse multi-variate temporal features with application to adverse drug event detection in medical records.

BMC medical informatics and decision making
BACKGROUND: Adverse drug events (ADEs) as well as other preventable adverse events in the hospital setting incur a yearly monetary cost of approximately $3.5 billion, in the United States alone. Therefore, it is of paramount importance to reduce the ...

A Group Decision Making Framework Based on Neutrosophic TOPSIS Approach for Smart Medical Device Selection.

Journal of medical systems
Advances in the medical industry has become a major trend because of the new developments in information technologies. This research offers a novel approach for estimating the smart medical devices (SMDs) selection process in a group decision making ...

Automatic lung nodule detection using multi-scale dot nodule-enhancement filter and weighted support vector machines in chest computed tomography.

PloS one
A novel CAD scheme for automated lung nodule detection is proposed to assist radiologists with the detection of lung cancer on CT scans. The proposed scheme is composed of four major steps: (1) lung volume segmentation, (2) nodule candidate extractio...

Computational prediction of diagnosis and feature selection on mesothelioma patient health records.

PloS one
BACKGROUND: Mesothelioma is a lung cancer that kills thousands of people worldwide annually, especially those with exposure to asbestos. Diagnosis of mesothelioma in patients often requires time-consuming imaging techniques and biopsies. Machine lear...

Deep learning for image analysis: Personalizing medicine closer to the point of care.

Critical reviews in clinical laboratory sciences
The precision-based revolution in medicine continues to demand stratification of patients into smaller and more personalized subgroups. While genomic technologies have largely led this movement, diagnostic results can take days to weeks to generate. ...

Computational Prediction of Human Disease- Associated circRNAs Based on Manifold Regularization Learning Framework.

IEEE journal of biomedical and health informatics
The accumulating evidences regarding circular RNAs (circRNAs) indicate that they play crucial roles in a wide range of biological processes and participate in tumorigenesis and progression. The number of newly discovered circRNAs have increased drama...