AIMC Topic: Humans

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Computational screening and in vitro evaluation of sphingosine-1-phosphate analogues as therapeutics for Non-Hodgkin's lymphoma.

Scientific reports
Non-Hodgkin's lymphoma (NHL) is a prevalent hematological malignancy that includes a variety of B-cell and T-cell proliferations. The S1P (sphingosine-1-phosphate) pathway, involved in cell survival, proliferation, and migration, plays a critical rol...

Machine learning classification of inflammatory bowel disease activity using white blood cell subsets.

BMJ open gastroenterology
OBJECTIVE: The lack of a rapid, validated, consistent test for tracking disease activity in patients with inflammatory bowel disease (IBD) is currently a major challenge. Currently used biomarkers have notable disadvantages, such as the slow processi...

Determining the Feasibility and Usability of a Co-Designed Culturally Appropriate Conversational Agent (DESI-Heart) to Support Self-Care in People With Cardiovascular Diseases: Protocol for a Single-Arm Pilot Trial.

JMIR research protocols
BACKGROUND: Cardiovascular diseases (CVDs) are a leading cause of death and disability worldwide. For people living with CVD, clinical guidelines recommend ongoing self-care such as symptom monitoring, medication adherence, and lifestyle modification...

Evaluation of an AI-Based Chatbot Providing Real-Time Feedback in Communication Training for Mental Health Care Professionals: Proof-of-Concept Observational Study.

Journal of medical Internet research
BACKGROUND: Effective communication is essential in medical practice, especially in dealing with the increasing number of patients presenting with mental health conditions. Feedback plays a crucial role in improving communication skills but is often ...

Comparison of ChatGPT and DeepSeek on a Standardized Audiologist Qualification Examination in Chinese: Observational Study.

JMIR formative research
BACKGROUND: Generative artificial intelligence (GenAI), exemplified by ChatGPT and DeepSeek, is rapidly advancing and reshaping human-computer interaction with its growing reasoning capabilities and broad applications across fields such as medicine a...

Climate stability and low population pressure predict peaceful interactions over 10,000 years of Central Andean history.

Science advances
As anthropogenic climate change threatens to destabilize global societies and ecosystems, anticipating likely human responses becomes ever more urgent. A key global initiative is the promotion of peaceful relations. Nonetheless, studies that systemat...

Machine Learning and Arrhythmia: Advances in Atrial Fibrillation Detection and Management.

Current atherosclerosis reports
PURPOSE OF REVIEW: In this paper we review recent advancements in the diagnosis and management of atrial fibrillation through machine learning (ML).

Center-surround inhibition in expectation and its underlying computational and artificial neural network models.

eLife
Expectation is beneficial for adaptive behavior through quickly deducing plausible interpretations of information. The profile and underlying neural computations of this process, however, remain unclear. When participants expected a grating with a sp...