Electronic health records (EHRs) contain critical information useful for clinical studies. Early assessment of patients' mortality in intensive care units is of great importance. In this paper, a Deep Rule-Based Fuzzy System (DRBFS) was proposed to d...
OBJECTIVES: We validate a machine learning-based sepsis-prediction algorithm () for the detection and prediction of three sepsis-related gold standards, using only six vital signs. We evaluate robustness to missing data, customisation to site-specifi...
Journal of pharmacokinetics and pharmacodynamics
Dec 30, 2017
Dexmedetomidine (DEX) is a fairly new alfa-agonist which has been increasingly used in recent years for analgosedation, mostly because it offers a unique ability of providing both moderate level of sedation and analgesia without respiratory depressio...
Journal of cardiothoracic and vascular anesthesia
Dec 11, 2017
OBJECTIVE: Patients with infective endocarditis undergoing cardiac surgery are a high-risk population. Few data on incidence and predictors of need for high-dose inotropic support in this setting are currently available.
PURPOSE: Genetic deletions decreasing serum alpha-Klotho (alpha-KL) have been associated with rapid aging, multi-organ failure and increased mortality in experimental sepsis. We hypothesized that lower alpha-KL obtained at the onset of septic shock c...
International journal of medical informatics
Oct 5, 2017
BACKGROUND: Mortality prediction of hospitalized patients is an important problem. Over the past few decades, several severity scoring systems and machine learning mortality prediction models have been developed for predicting hospital mortality. By ...
OBJECTIVES: To examine the feasibility of the automated creation of meaningful free-text summaries of longitudinal clinical records, using a new general methodology that we had recently developed; and to assess the potential benefits to the clinical ...
OBJECTIVES: Unplanned readmissions to the intensive care unit (ICU) are highly undesirable, increasing variance in care, making resource planning difficult and potentially increasing length of stay and mortality in some settings. Identifying patients...
The American journal of the medical sciences
Jul 1, 2017
Unexplained hypotension in the intensive care unit is commonly attributed to volume depletion, cardiorespiratory failure, sepsis, or relative adrenal insufficiency. In these acute conditions, thyroid hormone levels measured in blood, serum or plasma ...
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