AIMC Topic: Knowledge Bases

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Developed a knowledge base of risk factors for postoperative cognitive dysfunction: a retrospective database study.

Scientific reports
Postoperative cognitive dysfunction (POCD), a heterogeneous spectrum of surgery/anesthesia-associated neurocognitive impairments, represents a critical clinical challenge due to its associations with prolonged hospitalization, increased mortality, an...

Evaluating interdisciplinary research: Disparate outcomes for topic and knowledge base.

Proceedings of the National Academy of Sciences of the United States of America
Interdisciplinary research is essential for addressing complex global challenges, but there are concerns that scientific institutions like journals select against it. Prior work has focused largely on how interdisciplinarity relates to outcomes for p...

An extension to the OVH concept for knowledge-based dose volume histogram prediction in lung tumor volumetric-modulated arc therapy.

Journal of applied clinical medical physics
PURPOSE: Volumetric-modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs-at-risk (OARs). Particularly in the case of lung tumors, de...

Improving Dietary Supplement Information Retrieval: Development of a Retrieval-Augmented Generation System With Large Language Models.

Journal of medical Internet research
BACKGROUND: Dietary supplements (DSs) are widely used to improve health and nutrition, but challenges related to misinformation, safety, and efficacy persist due to less stringent regulations compared with pharmaceuticals. Accurate and reliable DS in...

The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques.

PLoS biology
Multiplexed imaging is a powerful approach in spatial biology, although it is complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, a central resource for reagents, protocols and more, to enhance knowledge sharing, optimiz...

PLSKB: An Interactive Knowledge Base to Support Diagnosis, Treatment, and Screening of Lynch Syndrome on the Basis of Precision Oncology.

JCO clinical cancer informatics
PURPOSE: Understanding the genetic heterogeneity of Lynch syndrome (LS) cancers has led to significant scientific advancements. However, these findings are widely dispersed across various resources, making it difficult for clinicians and researchers ...

ASVirus: A Comprehensive Knowledgebase for the Viral Alternative Splicing.

Journal of chemical information and modeling
Viruses are significant human pathogens responsible for pandemic outbreaks and seasonal epidemics. Viral infectious diseases impose a devastating global burden and have a profound impact on public health systems. During viral infections, alternative ...

A knowledge-based planning model to identify fraction-reduction opportunities in brain stereotactic radiotherapy.

Journal of applied clinical medical physics
OBJECTIVE: To develop and validate a HyperArc-based RapidPlan (HARP) model for three-fraction brain stereotactic radiotherapy (SRT) plans to then use to replan previously treated five-fraction SRT plans. Demonstrating the possibility of reducing the ...

Table tennis coaching system based on a multimodal large language model with a table tennis knowledge base.

PloS one
UNLABELLED: Table tennis is one of the most popular sports in the world, and it plays a positive role in the overall development of people's physical and mental health. This study develops an AI table tennis coaching system using a Multimodal Large L...

Empowering large language models for automated clinical assessment with generation-augmented retrieval and hierarchical chain-of-thought.

Artificial intelligence in medicine
BACKGROUND: Understanding and extracting valuable information from electronic health records (EHRs) is important for improving healthcare delivery and health outcomes. Large language models (LLMs) have demonstrated significant proficiency in natural ...