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Knowledge Bases

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Is it possible for knowledge-based planning to improve intensity modulated radiation therapy plan quality for planners with different planning experiences in left-sided breast cancer patients?

Radiation oncology (London, England)
BACKGROUND: Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with different planning experiences so fa...

NFPscanner: a webtool for knowledge-based deciphering of biomedical networks.

BMC bioinformatics
BACKGROUND: Many biological pathways have been created to represent different types of knowledge, such as genetic interactions, metabolic reactions, and gene-regulating and physical-binding relationships. Biologists are using a wide range of omics da...

Refining Automatically Extracted Knowledge Bases Using Crowdsourcing.

Computational intelligence and neuroscience
Machine-constructed knowledge bases often contain noisy and inaccurate facts. There exists significant work in developing automated algorithms for knowledge base refinement. Automated approaches improve the quality of knowledge bases but are far from...

Clinical implementation of a knowledge based planning tool for prostate VMAT.

Radiation oncology (London, England)
BACKGROUND: A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV overlap. The purpose of this...

Biological standards for the Knowledge-Based BioEconomy: What is at stake.

New biotechnology
The contribution of life sciences to the Knowledge-Based Bioeconomy (KBBE) asks for the transition of contemporary, gene-based biotechnology from being a trial-and-error endeavour to becoming an authentic branch of engineering. One requisite to this ...

ChloroKB: A Web Application for the Integration of Knowledge Related to Chloroplast Metabolic Network.

Plant physiology
Higher plants, as autotrophic organisms, are effective sources of molecules. They hold great promise for metabolic engineering, but the behavior of plant metabolism at the network level is still incompletely described. Although structural models (sto...

Assigning clinical codes with data-driven concept representation on Dutch clinical free text.

Journal of biomedical informatics
Clinical codes are used for public reporting purposes, are fundamental to determining public financing for hospitals, and form the basis for reimbursement claims to insurance providers. They are assigned to a patient stay to reflect the diagnosis and...