INTRODUCTION: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption.
This study examines the role of intellectual property protection (IPP) in enhancing radical technological innovation (RTI) within national research project teams, using an innovation-driven theory and an ability-motivation-opportunity (AMO) perspecti...
Journal of pharmaceutical and biomedical analysis
Jul 21, 2024
Lung cancer (LC) continues to be a leading death cause in China, primarily due to late diagnosis. This study aimed to evaluate the effectiveness of using plasma-based near-infrared spectroscopy (NIRS) for LC early diagnosis. A total of 171 plasma sam...
International journal of pharmaceutics
Jul 14, 2024
T-shaped partial least squares regression (T-PLSR) is a valuable machine learning technique for the formulation and manufacturing process development of new drug products. An accurate T-PLSR model requires experimental data with multiple formulations...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jul 11, 2024
The steady-state visual evoked potential (SSVEP) has become one of the most prominent BCI paradigms with high information transfer rate, and has been widely applied in rehabilitation and assistive applications. This paper proposes a least-square (LS)...
Quantitative Structure-Retention Relationship models were developed to identify phenolic compounds using a typical LC- system, with both UV and MS detection. A new chromatographic method was developed for the separation of fifty-two standard phenolic...
INTRODUCTION: Identifying the geographical origin of Gastrodia elata Blume contributes to the scientific and rational utilization of medicinal materials. In this study, infrared spectroscopy was combined with machine learning algorithms to distinguis...
The rapid and sensitive detection of pathogenic and suspicious bioaerosols are essential for public health protection. The impact of pollen on the identification of bacterial species by Raman and Fourier-Transform Infrared (FTIR) spectra cannot be ov...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jun 19, 2024
The sesquiterpene α-farnesene and its corresponding oxidation products, namely conjugated trienols (CTols) is well known to be correlated with the development of superficial scald, a typical physiological disorder after a long term of cold storage in...
Journal of chemical information and modeling
Jun 19, 2024
In this work, a new model with broad utility for quantitative spectroscopy development is reported. A primary objective of this work is to create a novel modeling procedure that may allow for higher automation of the model development process. The fu...
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