AIMC Topic: Leukemia

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An Enhanced Hyper-Parameter Optimization of a Convolutional Neural Network Model for Leukemia Cancer Diagnosis in a Smart Healthcare System.

Sensors (Basel, Switzerland)
Healthcare systems in recent times have witnessed timely diagnoses with a high level of accuracy. Internet of Medical Things (IoMT)-enabled deep learning (DL) models have been used to support medical diagnostics in real time, thus resolving the issue...

RCMNet: A deep learning model assists CAR-T therapy for leukemia.

Computers in biology and medicine
Acute leukemia is a type of blood cancer with a high mortality rate. Current therapeutic methods include bone marrow transplantation, supportive therapy, and chemotherapy. Although a satisfactory remission of the disease can be achieved, the risk of ...

An Automated View Classification Model for Pediatric Echocardiography Using Artificial Intelligence.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
BACKGROUND: View classification is a key step toward building a fully automated system for interpretation of echocardiograms. However, compared with adult echocardiograms, creating a view classification model for pediatric echocardiograms poses addit...

Explainable AI in Diagnosing and Anticipating Leukemia Using Transfer Learning Method.

Computational intelligence and neuroscience
White blood cells (WBCs) are blood cells that fight infections and diseases as a part of the immune system. They are also known as "defender cells." But the imbalance in the number of WBCs in the blood can be hazardous. Leukemia is the most common bl...

A Transfer-Learning-Based Deep Convolutional Neural Network for Predicting Leukemia-Related Phosphorylation Sites from Protein Primary Sequences.

International journal of molecular sciences
As one of the most important post-translational modifications (PTMs), phosphorylation refers to the binding of a phosphate group with amino acid residues like Ser (S), Thr (T) and Tyr (Y) thus resulting in diverse functions at the molecular level. Ab...

Blood cancer prediction using leukemia microarray gene data and hybrid logistic vector trees model.

Scientific reports
Blood cancer has been a growing concern during the last decade and requires early diagnosis to start proper treatment. The diagnosis process is costly and time-consuming involving medical experts and several tests. Thus, an automatic diagnosis system...

A deep learning method for counting white blood cells in bone marrow images.

BMC bioinformatics
BACKGROUND: Differentiating and counting various types of white blood cells (WBC) in bone marrow smears allows the detection of infection, anemia, and leukemia or analysis of a process of treatment. However, manually locating, identifying, and counti...

Automated detection of leukemia by pretrained deep neural networks and transfer learning: A comparison.

Medical engineering & physics
Leukemia is usually diagnosed by viewing the smears of blood and bone marrow using microscopes and complex Cytochemical tests can be used to authorize and classify leukemia. But these methods are costly, slow and affected by the proficiency and exper...

Identification of biomarkers for acute leukemia via machine learning-based stemness index.

Gene
Traditional methods to understand leukemia stem cell (LSC)'s biological characteristics include constructing LSC-like cells and mouse models by transgenic or knock-in methods. However, there are some potential pitfalls in using this method, such as r...

Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences.

Genome biology
Chromatin interactions play important roles in regulating gene expression. However, the availability of genome-wide chromatin interaction data is limited. We develop a computational method, chromatin interaction neural network (ChINN), to predict chr...