The American journal of sports medicine
Aug 15, 2025
BACKGROUND: Treatment decisions in patients with anterior cruciate ligament (ACL) injuries are influenced by multiple factors, such as the desire to return to sports or symptomatic instability. Identifying the differential treatment effect of ACL rec...
Childhood trauma constitutes a significant risk factor for adolescent anxiety, with emotion regulation playing a critical role. This large-scale longitudinal study (N = 2461 at baseline, with external validation) examined differential relationships b...
BACKGROUND: Alzheimer's disease (AD) is the principal cause of dementia and requires the early diagnosis of people with mild cognitive impairment (MCI) who are at high risk of progressing. Early diagnosis is imperative for optimizing clinical managem...
BACKGROUND: Hepatic encephalopathy (HE) contributes significantly to mortality among patients with liver cirrhosis. Early prediction of HE is essential for clinical decision-making, yet remains challenging-particularly in noncancer-related cirrhosis ...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Aug 6, 2025
The endogenous aspect of social influence, reflected in the spontaneous alignment of behaviors within close social relationships, plays a crucial role in understanding human social behavior. In two studies involving 222 human subjects (Study 1: = 17...
PURPOSE: Factors influencing missed appointments are complex and difficult to anticipate and intervene against. To optimize appointment adherence, we aimed to use personalized machine learning and big data analytics to predict the risk of and contrib...
BACKGROUND: Organoids have attracted enormous interest in disease modeling, drug screening, and precision medicine. However, developing robust patient-derived organoids (PDOs) was time-consuming, costly, and had low success rates for certain cancer t...
This study aims to identify depressive risks in elderly individuals with subjective cognitive decline (SCD) and develop a predictive model using machine learning algorithms to enable timely interventions.Data from the 2015 and 2018 waves of the China...
Although pesticide application is indispensable for agricultural productivity, improper use can pose significant health risks, particularly for vulnerable populations. This study investigated the effects of pesticide exposure on metabolic pathways an...
Rheumatoid arthritis (RA) is a systemic inflammatory condition posing challenges in identifying biomarkers for onset, severity and treatment responses. Here we investigate the plasma proteome in a longitudinal cohort of 278 RA patients, alongside 60 ...
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