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Lupus Erythematosus, Systemic

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Non-invasive prediction of the chronic degree of lupus nephropathy based on ultrasound radiomics.

Lupus
OBJECTIVE: Through machine learning (ML) analysis of the radiomics features of ultrasound extracted from patients with lupus nephritis (LN), this attempt was made to non-invasively predict the chronicity index (CI)of LN.

Artificial intelligence and high-dimensional technologies in the theragnosis of systemic lupus erythematosus.

The Lancet. Rheumatology
Systemic lupus erythematosus is a complex, systemic autoimmune disease characterised by immune dysregulation. Pathogenesis is multifactorial, contributing to clinical heterogeneity and posing challenges for diagnosis and treatment. Although strides i...

Exploration of machine learning methods to predict systemic lupus erythematosus hospitalizations.

Lupus
OBJECTIVES: Systemic lupus erythematosus (SLE) is a heterogeneous disease characterized by disease flares which can require hospitalization. Our objective was to apply machine learning methods to predict hospitalizations for SLE from electronic healt...

Comparing two machine learning approaches in predicting lupus hospitalization using longitudinal data.

Scientific reports
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by flares ranging from mild to life-threatening. Severe flares and complications can require hospitalizations, which account for most of the direct costs of SLE ca...

Profiling of kidney involvement in systemic lupus erythematosus by deep learning using the National Database of Designated Incurable Diseases of Japan.

Clinical and experimental nephrology
BACKGROUND: Kidney involvement frequently occurs in systemic lupus erythematosus (SLE), and its clinical manifestations are complicated. We profiled kidney involvement in SLE patients using deep learning based on data from the National Database of De...

Prediction of systemic lupus erythematosus-related genes based on graph attention network and deep neural network.

Computers in biology and medicine
Systemic lupus erythematosus (SLE) is an autoimmune disorder intricately linked to genetic factors, with numerous approaches having identified genes linked to its development, diagnosis and prognosis. Despite genome-wide association analysis and gene...

Systemic lupus in the era of machine learning medicine.

Lupus science & medicine
Artificial intelligence and machine learning applications are emerging as transformative technologies in medicine. With greater access to a diverse range of big datasets, researchers are turning to these powerful techniques for data analysis. Machine...

Early identification of macrophage activation syndrome secondary to systemic lupus erythematosus with machine learning.

Arthritis research & therapy
OBJECTIVE: The macrophage activation syndrome (MAS) secondary to systemic lupus erythematosus (SLE) is a severe and life-threatening complication. Early diagnosis of MAS is particularly challenging. In this study, machine learning models and diagnost...

Targeted metabolomics combined with machine learning to identify and validate new biomarkers for early SLE diagnosis and disease activity.

Clinical immunology (Orlando, Fla.)
BACKGROUND: The early diagnosis of systemic lupus erythematosus (SLE) and the assessment of disease activity progression remain a great challenge. Targeted metabolomics has great potential to identify new biomarkers of SLE.