Perceptions, thoughts, and actions unfold over millisecond timescales, while learned behaviors can require many days to mature. While recent experimental advances enable large-scale and long-term neural recordings with high temporal fidelity, it rema...
The development of coordinated reach-to-grasp movement has been well studied in infants and children. However, the role of motor cortex during this development is unclear because it is difficult to study in humans. We took the approach of using a bra...
OBJECTIVE: The aim of this work is to improve the state of the art for motor-control with a brain-machine interface (BMI). BMIs use neurological recording devices and decoding algorithms to transform brain activity directly into real-time control of ...
Under the goal-driven paradigm, Yamins et al. ( 2014 ; Yamins & DiCarlo, 2016 ) have shown that by optimizing only the final eight-way categorization performance of a four-layer hierarchical network, not only can its top output layer quantitatively p...
Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at macroscopic scales. Since for each pixel VSDi signals report the average membrane potential over hundreds of neurons, it seems natural to use a mean...
Brain decoders use neural recordings to infer the activity or intent of a user. To train a decoder, one generally needs to infer the measured variables of interest (covariates) from simultaneously measured neural activity. However, there are cases fo...
OBJECTIVE: Making mistakes is inevitable, but identifying them allows us to correct or adapt our behavior to improve future performance. Current brain-machine interfaces (BMIs) make errors that need to be explicitly corrected by the user, thereby con...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nov 8, 2017
Complex cognitive behaviors, such as context-switching and rule-following, are thought to be supported by the prefrontal cortex (PFC). Neural activity in the PFC must thus be specialized to specific tasks while retaining flexibility. Nonlinear "mixed...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jun 1, 2017
Brain-machine interface (BMI) systems use signals acquired from the brain to directly control the movement of an actuator, such as a computer cursor or a robotic arm, with the goal of restoring motor function lost due to injury or disease of the nerv...
Decision making involves dynamic interplay between internal judgements and external perception, which has been investigated in delayed match-to-category (DMC) experiments. Our analysis of neural recordings shows that, during DMC tasks, LIP and PFC ne...