Determining the catalytic residues in an enzyme is critical to our understanding the relationship between protein sequence, structure, function, and enhancing our ability to design novel enzymes and their inhibitors. Although many enzymes have been s...
Cyclin-dependent kinase (CDK) is an interesting biological macromolecule due to its role in cell cycle progression, transcription control, and neuronal development, to mention the most studied biological activities. Furthermore, the availability of h...
False-positive assay readouts caused by badly behaving compounds-frequent hitters, pan-assay interference compounds (PAINS), aggregators, and others-continue to pose a major challenge to experimental screening. There are only a few in silico methods ...
Journal of the American College of Radiology : JACR
Feb 1, 2018
Enterprise imaging has channeled various technological innovations to the field of clinical radiology, ranging from advanced imaging equipment and postacquisition iterative reconstruction tools to image analysis and computer-aided detection tools. Mo...
Journal of the American College of Radiology : JACR
Feb 1, 2018
Enterprise imaging has channeled various technological innovations to the field of clinical radiology, ranging from advanced imaging equipment and postacquisition iterative reconstruction tools to image analysis and computer-aided detection tools. Mo...
Recent technological advances in machine learning offer the possibility of decoding complex datasets and discern latent patterns. In this study, we adopt Liquid State Machines (LSM) to recognize the emotional state of an individual based on EEG data....
Prevention and diagnosis of NAFLD is an ongoing area of interest in the healthcare community. Screening is complicated by the fact that the accuracy of noninvasive testing lacks specificity and sensitivity to make and stage the diagnosis. Currently n...
PURPOSE: Breathing sounds during sleep are altered and characterized by various acoustic specificities in patients with sleep disordered breathing (SDB). This study aimed to identify acoustic biomarkers indicative of the severity of SDB by analyzing ...
Theoretical biology & medical modelling
Feb 1, 2018
Early prediction of seasonal epidemics such as influenza may reduce their impact in daily lives. Nowadays, the web can be used for surveillance of diseases. Search engines and social networking sites can be used to track trends of different diseases ...
This paper presents a novel method for salient object detection in nature image by simulating microsaccades in fixational eye movements. Due to a nucleated cell usually stained that is salient obviously, the proposed method is suitable to segment nuc...
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