AIMC Topic: Machine Learning

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Primary care research on hypertension: A bibliometric analysis using machine-learning.

Medicine
Hypertension is one of the most important chronic diseases worldwide. Hypertension is a critical condition encountered frequently in daily life, forming a significant area of service in Primary Health Care (PHC), which healthcare professionals often ...

A framework of multi-view machine learning for biological spectral unmixing of fluorophores with overlapping excitation and emission spectra.

Briefings in bioinformatics
The accuracy of assigning fluorophore identity and abundance, known as spectral unmixing, in biological fluorescence microscopy images remains a significant challenge due to the substantial overlap in emission spectra among fluorophores. In tradition...

KPRR: a novel machine learning approach for effectively capturing nonadditive effects in genomic prediction.

Briefings in bioinformatics
Nonadditive genetic effects pose significant challenges to traditional genomic selection methods for quantitative traits. Machine learning approaches, particularly kernel-based methods, offer promising solutions to overcome these limitations. In this...

Machine learning-enabled virtual screening indicates the anti-tuberculosis activity of aldoxorubicin and quarfloxin with verification by molecular docking, molecular dynamics simulations, and biological evaluations.

Briefings in bioinformatics
Drug resistance in Mycobacterium tuberculosis (Mtb) is a significant challenge in the control and treatment of tuberculosis, making efforts to combat the spread of this global health burden more difficult. To accelerate anti-tuberculosis drug discove...

Dual-stage optimizer for systematic overestimation adjustment applied to multi-objective genetic algorithms for biomarker selection.

Briefings in bioinformatics
The selection of biomarker panels in omics data, challenged by numerous molecular features and limited samples, often requires the use of machine learning methods paired with wrapper feature selection techniques, like genetic algorithms. They test va...

Annotating publicly-available samples and studies using interpretable modeling of unstructured metadata.

Briefings in bioinformatics
Reusing massive collections of publicly available biomedical data can significantly impact knowledge discovery. However, these public samples and studies are typically described using unstructured plain text, hindering the findability and further reu...

Comprehensive bioinformatics and machine learning analyses for breast cancer staging using TCGA dataset.

Briefings in bioinformatics
Breast cancer is an alarming global health concern, including a vast and varied set of illnesses with different molecular characteristics. The fusion of sophisticated computational methodologies with extensive biological datasets has emerged as an ef...

FunlncModel: integrating multi-omic features from upstream and downstream regulatory networks into a machine learning framework to identify functional lncRNAs.

Briefings in bioinformatics
Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play important roles in molecular and cellular biology. Although many algorithms have been developed to reveal their associations with complex diseases by using downstream targets, th...

AutoXAI4Omics: an automated explainable AI tool for omics and tabular data.

Briefings in bioinformatics
Machine learning (ML) methods offer opportunities for gaining insights into the intricate workings of complex biological systems, and their applications are increasingly prominent in the analysis of omics data to facilitate tasks, such as the identif...

Handwritten Data Extraction Using OpenAI ChatGPT4o and Robotic Process Automation.

Studies in health technology and informatics
This paper proposes to create an Robotic Process Automation style application that can digitalize and extract data from handwritten medical forms. The RPA robot uses OpenAI ChatGPT4o model to extract handwritten medical data and transform it into typ...