AIMC Topic: Machine Learning

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Explainable machine learning model based on EEG, ECG, and clinical features for predicting neurological outcomes in cardiac arrest patient.

Scientific reports
Early and accurate prediction of neurological outcomes in comatose patients following cardiac arrest is critical for informed clinical decision-making. Existing studies have predominantly focused on EEG for assessing brain injury, with some exploring...

5-Repurposed Drug Candidates Identified in Motor Neurons and Muscle Tissues with Amyotrophic Lateral Sclerosis by Network Biology and Machine Learning Based on Gene Expression.

Neuromolecular medicine
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that leads to motor neuron degeneration, muscle weakness, and respiratory failure. Despite ongoing research, effective treatments for ALS are limited. This study aimed to...

Machine learning-based non-invasive continuous dynamic monitoring of human core temperature with wearable dual temperature sensors.

Physiological measurement
Due to the growing demand for personal health monitoring in extreme environments, continuous monitoring of core temperature has become increasingly important. Traditional monitoring methods, such as mercury thermometers and infrared thermometers, may...

Combining High-Throughput Screening and Machine Learning to Predict the Formation of Both Binary and Ternary Amorphous Solid Dispersion Formulations for Early Drug Discovery and Development.

Pharmaceutical research
OBJECTIVE: Amorphous solid dispersion (ASD) is widely utilized to enhance the solubility and bioavailability of water-insoluble drugs. However, conventional experimental approaches for ASD development are often resource-intensive and time-consuming. ...

Integrating multiple spatial transcriptomics data using community-enhanced graph contrastive learning.

PLoS computational biology
Due to the rapid development of spatial sequencing technologies, large amounts of spatial transcriptomic datasets have been generated across various technological platforms or different biological conditions (e.g., control vs. treatment). Spatial tra...

Tackling Modality-Heterogeneous Client Drift Holistically for Heterogeneous Multimodal Federated Learning.

IEEE transactions on medical imaging
Multimodal Federated Learning (MFL) has emerged as a collaborative paradigm for training models across decentralized devices, harnessing various data modalities to facilitate effective learning while respecting data ownership. In this realm, notably,...

DEeR: Deviation Eliminating and Noise Regulating for Privacy-Preserving Federated Low-Rank Adaptation.

IEEE transactions on medical imaging
Integrating low-rank adaptation (LoRA) with federated learning (FL) has received widespread attention recently, aiming to adapt pretrained foundation models (FMs) to downstream medical tasks via privacy-preserving decentralized training. However, owi...

HMIL: Hierarchical Multi-Instance Learning for Fine-Grained Whole Slide Image Classification.

IEEE transactions on medical imaging
Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological variations within...

Unlocking the Potential of Weakly Labeled Data: A Co-Evolutionary Learning Framework for Abnormality Detection and Report Generation.

IEEE transactions on medical imaging
Anatomical abnormality detection and report generation of chest X-ray (CXR) are two essential tasks in clinical practice. The former aims at localizing and characterizing cardiopulmonary radiological findings in CXRs, while the latter summarizes the ...

MT-CooL: Multi-Task Cooperative Learning via Flat Minima Searching.

IEEE transactions on medical imaging
While multi-task learning (MTL) has been widely developed for natural image analysis, its potential for enhancing performance in medical imaging remains relatively unexplored. Most methods formulate MTL as a multi-objective problem, inherently forcin...