AIMC Topic: Mice
Clear Filters Showing 461 to 470 of 1502 articles
Discovery of a structural class of antibiotics with explainable deep learning.
Nature
Dec 20, 2023
The discovery of novel structural classes of antibiotics is urgently needed to address the ongoing antibiotic resistance crisis. Deep learning approaches have aided in exploring chemical spaces; these typically use black box models and do not provide...
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58.
Journal of lipid research
Dec 20, 2023
Lipolysis is an essential metabolic process that releases unesterified fatty acids from neutral lipid stores to maintain energy homeostasis in living organisms. Adipose triglyceride lipase (ATGL) plays a key role in intracellular lipolysis and can be...
High-Yield Preparation of American Oyster Defensin (AOD) via a Small and Acidic Fusion Tag and Its Functional Characterization.
Marine drugs
Dec 20, 2023
The marine peptide, American oyster defensin (AOD), is derived from and exhibits a potent bactericidal effect. However, recombinant preparation has not been achieved due to the high charge and hydrophobicity. Although the traditional fusion tags suc...
A machine learning approach for quantifying age-related histological changes in the mouse kidney.
GeroScience
Dec 16, 2023
The ability to quantify aging-related changes in histological samples is important, as it allows for evaluation of interventions intended to effect health span. We used a machine learning architecture that can be trained to detect and quantify these ...
Rapid visualization of PD-L1 expression level in glioblastoma immune microenvironment via machine learning cascade-based Raman histopathology.
Journal of advanced research
Dec 10, 2023
INTRODUCTION: Combination immunotherapy holds promise for improving survival in responsive glioblastoma (GBM) patients. Programmed death-ligand 1 (PD-L1) expression in immune microenvironment (IME) is the most important predictive biomarker for immun...
O-GlcNAcPRED-DL: Prediction of Protein O-GlcNAcylation Sites Based on an Ensemble Model of Deep Learning.
Journal of proteome research
Dec 6, 2023
O-linked β--acetylglucosamine (O-GlcNAc) is a post-translational modification (i.e., O-GlcNAcylation) on serine/threonine residues of proteins, regulating a plethora of physiological and pathological events. As a dynamic process, O-GlcNAc functions i...
Lateral flexion of a compliant spine improves motor performance in a bioinspired mouse robot.
Science robotics
Dec 6, 2023
A flexible spine is critical to the motion capability of most animals and plays a pivotal role in their agility. Although state-of-the-art legged robots have already achieved very dynamic and agile movement solely relying on their legs, they still ex...
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Journal of advanced research
Dec 2, 2023
INTRODUCTION: Synthetic lethality (SL) provides an opportunity to leverage different genetic interactions when designing synergistic combination therapies. To further explore SL-based combination therapies for cancer treatment, it is important to ide...
MaTPIP: A deep-learning architecture with eXplainable AI for sequence-driven, feature mixed protein-protein interaction prediction.
Computer methods and programs in biomedicine
Nov 30, 2023
BACKGROUND AND OBJECTIVE: Protein-protein interaction (PPI) is a vital process in all living cells, controlling essential cell functions such as cell cycle regulation, signal transduction, and metabolic processes with broad applications that include ...
Dual-Stream Spatiotemporal Networks with Feature Sharing for Monitoring Animals in the Home Cage.
Sensors (Basel, Switzerland)
Nov 30, 2023
This paper presents a spatiotemporal deep learning approach for mouse behavioral classification in the home-cage. Using a series of dual-stream architectures with assorted modifications for optimal performance, we introduce a novel approach that joi...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31137
- Neural Networks, Computer 29769
- Algorithms 26908
- Deep Learning 26418
- Artificial Intelligence 24354
- Robotics 13322
- Image Processing, Computer-Assisted 9552
- Retrospective Studies 9136
- Magnetic Resonance Imaging 6198
- Reproducibility of Results 5602
- Tomography, X-Ray Computed 4778
- Support Vector Machine 4695
- Computational Biology 4246
- Brain 4056
- Computer Simulation 3887
Recent Journals
- Scientific reports 6082
- Sensors (Basel, Switzerland) 4794
- PloS one 4044
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1868
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1137
- Journal of chemical information and modeling 1006
- Nature communications 959
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 829