AIMC Topic: Microbiota

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Harnessing machine learning for metagenomic data analysis: trends and applications.

mSystems
Metagenomic sequencing has revolutionized our understanding of microbial ecosystems by enabling high-resolution profiling of microbes across diverse environments. However, the resulting data are high-dimensional, sparse, and noisy, posing challenges ...

Building Predictive Understanding of the Activated Sludge Microbiome by Bridging Microbial Growth Kinetics and Microbial Population Dynamics.

Environmental science & technology
Modeling microbiomes can provide predictive insights into microbial ecology, but current modeling approaches suffer from inherent limitations. In this study, a novel modeling approach was developed based on the intrinsic connection between the growth...

Post-COVID-19 disruption of the respiratory microbiome modulates : a multi-center retrospective investigation study.

Emerging microbes & infections
Since the COVID-19 pandemic, there has been a notable resurgence of pneumonia (MPP) in children, with a concerning rise in the severity of cases. Although changes in post-pandemic respiratory infection patterns have been documented, the reasons behi...

Predicting rhizosphere-competence-related catabolic gene clusters in plant-associated bacteria with rhizoSMASH.

Nature communications
Plants release a substantial fraction of their photosynthesized carbon into the rhizosphere as root exudates that drive microbiome assembly. Deciphering how plants modulate the composition and activities of rhizosphere microbiota through root exudate...

Global wastewater microbiome reveals core bacterial community and viral diversity with regional antibiotic resistance patterns.

mSystems
Municipal wastewater treatment plants (WWTPs) serve as global repositories for diverse and dynamic microbial communities, reflecting the complex interplay of human activities, environmental conditions, and public health challenges. Despite their impo...

Viral community succession during cadaver decomposition and its potential for estimating postmortem intervals.

Applied and environmental microbiology
UNLABELLED: Microbial communities play a vital role in cadaver decomposition and serve as reliable tools for postmortem interval (PMI) estimation. However, current research focuses primarily on bacterial/fungal communities, though viruses-as Earth's ...

Effect of immune-related intratumoral microbiota and host gene expression on cancer prognosis.

mSystems
UNLABELLED: The intratumoral microbiota has been identified as an indispensable part of the tumor microenvironment (TME). However, the relationship between the intratumoral microbiota and host gene expression, as well as its impact on prognosis and T...

Metagenomic research on the structural difference of plaque microbiome from different caries stages and the construction of a caries diagnostic model.

mSystems
Development of dental caries is a dynamic process; yet, there is limited knowledge on microbial differences at various stages of caries at higher resolution. To investigate the shifting microbiome profiles across different caries stages, 30 children ...

Integrated Microbiome Data Analysis Reveals Potential Pneumonia Microbial Biomarkers in ICU Patients: A Machine Learning Approach.

Current microbiology
The human microbiome is pivotal in maintaining health and managing diseases. By examining the core microbiome in intensive care units (ICU) patients with pneumonia, we can gain valuable insights into the microbial communities associated with disease ...

New insights into soil bacteria communities in Beijing urban greenspace based on urbanization gradient.

The Science of the total environment
Research on urban soils has traditionally neglected two significant dimensions: the spatial heterogeneity emerging within megacity resulting from varying urbanization rates, and the dynamic responses of soil microbial communities to ongoing urban exp...