AIMC Topic: Microfluidic Analytical Techniques

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Machine learning-enabled microfluidic ratiometric fluorescence sensor array based on lanthanide-gold nanoclusters for visual detection of multicomponent antibiotics.

Biosensors & bioelectronics
The accumulation of multiple antibiotics in the environment poses severe threats to ecosystems and human health, demanding rapid, sensitive, and portable detection methods. This study introduces a lanthanide-gold nanocluster (AuNCs)-based microfluidi...

A digital fluorescence immunoassay platform using a self-driven microfluidic cartridge with magnetic capture.

Biosensors & bioelectronics
Self-driven microfluidic devices have significantly advanced point-of-care testing (POCT) by enabling integration and automation of all the components required for biochemical analysis through capillary-driven fluid flow, eliminating the need for ext...

Wearable microfluidic devices for multiplex body fluid monitoring.

The Analyst
Wearable microfluidic devices enable multiplexed, continuous monitoring of analytes in body fluids such as sweat, interstitial fluid, tears, and saliva, providing comprehensive data for personalized health management and disease diagnosis. These devi...

StratoLAMP-2: A Microfluidics-Free, Deep-Learning Platform for Multiplex Digital Molecular Diagnostics.

Analytical chemistry
Accurate and accessible molecular diagnostics are critical for early disease detection, infection control, and personalized medicine. Digital nucleic acid testing offers absolute quantification by isolating individual amplification events into discre...

Microfluidic-assisted analysis of extracellular vesicles for advanced biomedical applications.

Chemical communications (Cambridge, England)
Extracellular vesicles are lipid bilayer-enclosed nanoparticles that play a crucial role in intercellular communication by transporting bioactive molecules across cells, tissues, and even organisms. Although certain aspects of EV biogenesis, function...

Wearable and implantable microfluidic technologies for future digital therapeutics.

Lab on a chip
Microfluidic technology, originally developed for lab-on-a-chip applications, has rapidly expanded into wearable and implantable biomedical systems, enabling precise fluid handling for real-time biosensing, targeted drug delivery, and closed-loop the...

YOLOv5-aided paper-based microfluidic intelligent sensing platform for multiplex sweat biomarker analysis.

Biosensors & bioelectronics
Sweat, a biofluid rich in various biomarkers, offers significant potential for non-invasive health monitoring and disease screening. Colorimetric detection is well-suited for multi-analyte quantification and point-of-care testing in sweat analysis, w...

Characterizing ssRNA and dsRNA electrophoretic behavior: empirical insights with neural network-aided predictions.

The Analyst
RNA-based therapeutics are currently at the forefront of the biopharmaceutical industry because of their safety, efficacy, and shortened time from disease discovery to therapy development. Microfluidic electrophoresis provides a great analytical plat...

AI-CMCA: a deep learning-based segmentation framework for capillary microfluidic chip analysis.

Scientific reports
Capillary microfluidic chips (CMCs) enable passive liquid transport via surface tension and wettability gradients, making them central to point-of-care diagnostics and biomedical sensing. However, accurate analysis of capillary-driven flow experiment...

Advanced droplet microfluidic platform for high-throughput screening of industrial fungi.

Biosensors & bioelectronics
Industrial fungi are pivotal candidates for the production of a diverse array of bioproducts. To enhance their productivity, these strains are frequently subjected to genetic modifications. Following transformation, the selection of optimal productio...